To The Editor: To elucidate the mechanism of granulocyte damage during FL, studies have been reported of the interaction between nylon-wool fibers and isolated granulocytes suspended in protein free media,’2 in 5% plasma,2 or in 1% human serum albumin.3 In FL, however, heparinized whole blood is passed through a nylon-wool filter, resulting in plasma protein coating of the fibers within seconds...

OBJECTIVES We performed a cytotoxicity study by cell magnetometry, measured lactate dehydrogenase (LDH) activity by enzyme assay, detected DNA ladder formation, and performed morphological examination by electron microscopy in order to evaluate the safety of high temperature wool (HT wool), an asbestos substitute, using long and short chrysotile fibers (CF) as positive controls and phosphate bu...

In this study, we analyzed the effects of synthetic vitreous fibers (SVFs) on a mesothelial (MeT5A) and a fibroblast cell line (NIH3T3), compared to those exerted by crocidolite asbestos fibers. SVFs (glass wool, rock wools) do not induce significant changes in cell mortality, whereas crocidolite asbestos fibers caused a dose-dependent cytotoxicity. We investigated the correlation between the f...

We conducted three experiments to evaluate the Optical Fibre Diameter Analyser (OFDA) for estimating medullation (med [M], kemp [K], and total [T] medullated fiber content) in mohair and wool produced by Angora goats and sheep, respectively. Medullation can be a beneficial characteristic in certain types of wool, but it is highly undesirable in mohair and apparel wools. Current techniques for e...

Characterization of compositionally-complex aluminosilicate glass particles and fibers such as stone wool, their interfaces with water ions, is significant to a range areas regarding dissolution phenomena. Knowledge atomic level structures these critical elucidating traits. Molecular simulations can provide details, complementing experimental efforts. However, prediction the structure wool fibe...