BACKGROUND Mechanical forces play an important role in tissue neovascularization and are a constituent part of modern wound therapies. The mechanisms by which vacuum assisted closure (VAC) modulates wound angiogenesis are still largely unknown. OBJECTIVE To investigate how VAC treatment affects wound hypoxia and related profiles of angiogenic factors as well as to identify the anatomical char...

background thermal injury is associated with several biochemical and histopathological alteration in tissue. analysis of these objective parameters in research and clinical field are common to determine healing rate of burn wound. negative pressure wound therapy has been achieved wide success in treating chronic wounds. this study determines superficial burn wound healing with intermittent nega...

A phosphorylated form of cotton gauze for treatment of chronic wounds was designed to improve the wound dressing’s capacity to remove harmful proteases from the wound and facilitate healing. Development of the fabric finishing chemistry of the wound dressing with a process suitable for textile mill production required adapting the stationary finishing chemistry of the cotton phosphorylation fro...

Wound complications following surgical resection in patients treated with neoadjuvant chemoradiation therapy are common and can be a difficult problem to manage. Negative pressure dressing technology appears to be safe and effective in the treatment of radiation-associated wound complications and can be used in the outpatients clinic setting. The presented case demonstrates that negative pressu...

There is a wide range of dressings classified as ‘foam dressings’; however, there can be substantial differences in the chemical makeup of different foam dressings. Sussman (2010) distinguishes foams into two separate groups, those being a ‘true foam’ that draws fluid into air spaces, or ‘pseudo-foam’ that draws in fluid and physically expands as it retains it. True foams contain hydrophilic po...

A novel cross-linked honey hydrogel dressing was developed by incorporating Malaysian honey into hydrogel dressing formulation, cross-linked and sterilized using electron beam irradiation (25 kGy). In this study, the physical properties of the prepared honey hydrogel and its wound healing efficacy on deep partial thickness burn wounds in rats were assessed. Skin samples were taken at 7, 14, 21,...

Surgery for thumb polydactyly is a commonly performed orthopaedic procedure in Asia Pacific region. Despite extensive publications on topical dressing methods and dressing materials in paediatric wounds, there is no single design that affords a secure and yet comfortable post-operative wound dressing for thumb polydactyly. We have devised a new dressing method, which can easily be fabricated fo...

It has been seen in recent years, that an increasing number of patients are being discharged early into the community, to be managed by the district or practice nurse. This has been especially the case with surgical patients, a consequence of this being that the nurse has to manage their wound post-operatively. For a patient with a cavity wound this presents further difficulties as many of the ...

INTRODUCTION Most surgical wounds are closed primarily, but some are allowed to heal by secondary intention. This usually involves repeated packing and dressing of the raw wound surfaces. Although the long-term care of such wounds has devolved to the care of nurses in the community or out-patient setting, the initial wound dressing or cavity packing is done by the surgeon in the operating theat...

An injury to the skin resulting in a wound starts the complex healing machinery of the body, normally leading to rapid wound closure. In some cases the normal wound healing process is disturbed and prolonged; which can lead to chronic, non-healing wounds such as venous leg ulcers. Chronic wounds in general are estimated to affect 1 – 2 % of the world’s population, and about 1 % is suffering fro...