Acute infection of surgical incision sites often requires specialized wound care in preparation for surgical closure. Optimal therapy for preparing such wounds for a secondary closure procedure remains uncertain. The authors report wound outcomes after administering acoustic pressure wound therapy in conjunction with negative pressure wound therapy with reticulated open-cell foam dressing chang...

BACKGROUND Superficial surgical site infection (SSI) can be caused by bacterial invasion during surgery. We investigated whether bacteria are found at the wound margin during surgery and whether a wound protector (WP; Alexis® Wound Retractor; Applied Medical, Rancho Santa Margarita, CA) contributes to preventing invasion of the incision margin. METHODS We studied 272 patients who underwent ga...

Objectives: Median sternotomy is the incision of choice for most cardiac surgical procedures, but the full-length vertical skin incision generally leaves an unsightly scar. In certain patients undergoing short, low-risk procedures, cosmetic considerations are of relatively greater importance. Methods: A minimal transverse curvilinear skin incision with low median sternotomy is described which g...

Garlic extract is gaining increasing acceptance as an antimicrobial and anti-inflammatory agent and as a folk remedy on wound healing. We studied the effect of crushed garlic extract on wound healing in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups, as control and treatment. Animals of control g...

BACKGROUND New endovascular techniques facilitate treatment of complex deep vein obstructions in cases of post-thrombotic syndrome. In a relevant number of these patients, endophlebectomy including the implantation of an arteriovenous fistula between the common femoral artery and the femoral vein is indispensable in order to establish a good inflow. These procedures display a high risk of wound...

The leaves of Carapa guianensis have been used to treat ulcers, skin parasites, and skin problems. The ethanolic extract of C. guianensis leaf was evaluated for its antibacterial and wound healing activity using excision, incision and dead space wound models in rats. The animals were randomly divided into two groups (n = 6) in all the models. In the excision wound model test group animals were ...

While transverse incision is the recommended entry technique for cesarean delivery in high-income countries, it is our experience that midline incision is still used routinely in many low-income settings. Accordingly, international guidelines lack uniformity on this matter. Although evidence is limited, the literature suggests important advantages of the transverse incision, with lower risk of ...

BACKGROUND Establishment of early oral nutrition after surgery is associated with a decrease in morbidity and mortality. The following studies were undertaken to determine how surgery influences food-reinforced behavior in rats and to determine the relevance of afferent input from the incision site on this behavior. METHODS Rats were trained to press a lever for food pellets to assess the eff...

Natural products have numerous medicinal applications and play important roles in the biology of the organisms that accumulate them. Flavonoids are one large group of natural products with a diverse number of functions in plants and in human health. The isolates of the flowers of Ipomoea carnea (Family: Convolvulaceae) was screened for wound-healing activity on the male wistar rats by Excision ...

Morinda citrifolia (Noni) has been traditionally used for bone and wound healing.   The present study was carried out to investigate the effect of Morinda citrifolia leaves on experimental wounds and lipid peroxide levels in rats. Effect of aqueous extract of leaves of Morinda citrifolia (200 mg/kg) on excision, resutured incision and dead space wound models were studied. Measurement...