Water-restricted (WR) rats exhibit a rapid suppression of plasma corticosterone following drinking. The present study monitored Fos-like immunoreactivity (Fos) to assess the effect of WR-induced drinking on the activity of vasopressin (VP)-positive magnocellular and parvocellular neurons and corticotropin-releasing hormone (CRH)-positive parvocellular neurons in the paraventricular nucleus of t...

New NTT/SOFI near-IR narrow-band imaging and spectroscopy reveals an additional four Wolf-Rayet (WR) stars in the massive cluster Westerlund 1, bringing the total WR population to 24. Sixteen of the WR stars in Wd1 have been classified WN5–11, while eight are WC8–9. An observed WR to RSG/YHG ratio of ∼3 suggests an age of 4.5–5.0 Myr, with WR stars descended from 40–55M⊙ progenitors. On the bas...

Wolf-Rayet (WR) stars are the chemically evolved descendents of O stars, such that they trace massive star formation. Here we present results of recent VLT/FORS surveys of WR stars in near by spiral and irregular galaxies and consider individual WR stars as progenitors of Type Ib/c core-collapse supernovae. Young massive clusters hosting large WR populations may be used as templates for high-re...

OBJECTIVE We examined the relationship among the serum omega-3 and omega-6 fatty acid (O3FA and O6FA) levels, serum C-reactive protein (CRP) levels, and arterial stiffness/wave reflection (AS/WR) in healthy Japanese men. METHODS In 2206 Japanese healthy men, parameters related to the AS/WR (i.e., brachial-ankle pulse wave velocity and radial arterial pulse wave analysis) were measured. RESU...

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Among the other dwarf galaxies with violent star formation IC10 galaxy stands out for anomalously high number of Wolf-Rayet (WR) stars. For instance, the number of WR-stars in IC10 is 20 times higher than that in LMC and spatial density of WR stars in IC10 reaches 11 WR stars per square kpc (Massey et al., 2002 [8], Massey et al., 2007 [7], Crowther et al., 2003 [4] and references in these pape...

Dipeptides absorbed by the intestinal epithelium are delivered to circulation, but their metabolic roles are not yet clearly understood. We investigated the biological activities of a dietary dipeptide, H-Trp-Arg-OH (WR), on the regulation of peroxisome proliferator-activated receptor (PPAR) α activity. Reporter gene assays revealed that WR dose-dependently induced PPARα transactivation. Surfac...