Islet function was examined in 13 severely obese women [body mass index 46.4 +/- 5.5 (SD) kg/m(2)] before and after standardized 15 and 25% weight reduction (WR) instituted by bariatric surgery. The insulin response to arginine at fasting (AIR(1)), at 14 mmol/l, and at >25 mmol/l glucose was reduced by 37-50% after 15 and 25% WR (P <or= 0.05). Insulin sensitivity was determined as the amount of...

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World records (WR) in sports illustrate the ultimate expression of human integrated muscle biology, through speed or strength performances. Analysis and prediction of man's physiological boundaries in sports and impact of external (historical or environmental) conditions on WR occurrence are subject to scientific controversy. Based on the analysis of 3263 WR established for all quantifiable off...

STUDY OBJECTIVES The purpose of this study was to determine the reliability of two respiratory therapy self-assessment examinations: the written registry examination (WR), and the clinical simulation examination (CSE). We then used reliability coefficients to test the true correlation between the WR and CSE by employing the Spearman-Brown formula to attenuate for unreliability. DESIGN This wa...

The Rice-500 Leydig cell tumor (LCT) in Fischer rats is a model of humoral hypercalcemia of malignancy (HHM). In this model, the elevation of plasma calcium (Ca) does not result merely from an increased bone resorption, but also from an enhanced tubular Ca reabsorption (TRCa). We investigated the hypocalcemic response to WR-2721 [S-2,2-(3-aminopropylamino)-, ethylphosphorothioic acid] in LCT-be...

This paper critiques the work and thesis of Judy Wood and Morgan Reynolds suggesting that a "Star Wars" beam weapon was used in the destruction of the World Trade Center towers (referred to herein as the “WR thesis” or “WR paper”). The WR thesis is presented in a web-based paper entitled “The Star Wars Beam Weapon”, which can be found here. The central claim of the WR thesis is that the phenome...

We demonstrate that it is crucial to account for the evolution of the starburst population in order to derive reliable numbers of O stars from integrated spectra for burst ages t > 2−3 Myr. In these cases the method of Vacca & Conti (1992) and Vacca (1994) systematically underestimates the number of O stars. Therefore the current WR/O number ratios in Wolf–Rayet (WR) galaxies are overestimated....

The precise immune components required for protection against a respiratory Orthopoxvirus infection, such as human smallpox or monkeypox, remain to be fully identified. In this study, we used the virulent Western Reserve strain of vaccinia virus (VACV-WR) to model a primary respiratory Orthopoxvirus infection. Naive mice infected with VACV-WR mounted an early CD8 T cell response directed agains...

Biomedical Named Entity Recognition (BNER), which extracts important entities such as genes and proteins, is a crucial step of natural language processing in the biomedical domain. Various machine learning-based approaches have been applied to BNER tasks and showed good performance. In this paper, we systematically investigated three different types of word representation (WR) features for BNER...