KIDNEY transplantation has improved tremendously over the past decades. After the introduction of cyclosporine (CyA), delayed graft function and surgical complications became the most important prognostic factors. Early diagnosis and management can save the grafted kidney and prevent life-threatening complications. We investigated the surgical complications in 1000 kidney transplantations at ou...

The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation by sequencing at a level that should allow the genome-wide detection of most variants with frequencies as low as 1%. However, in the major histocompatibility complex (MHC), only the top 10 most frequent haplotypes are in the 1% frequency range whereas thousands of haplotypes are present at lower ...

The 1000 Genomes Project created a valuable, worldwide reference for human genetic variation. Common uses of the 1000 Genomes dataset include genotype imputation supporting Genome-wide Association Studies, mapping expression Quantitative Trait Loci, filtering non-pathogenic variants from exome, whole genome and cancer genome sequencing projects, and genetic analysis of population structure and ...

The giant radar/radio astronomy dish near Arecibo, Puerto Rico, was conceived by William E. Gordon in early 1958 as a back-scattering radar system to measure the density and temperature of the Earth’s ionosphere up to a few thousand kilometers. Gordon calculated the required size of the antenna by using the Thomson crosssection for scattering by the electrons, and assuming that the elementary s...

Improved survival of very pre-term infants is a result of advances in obstetric and neonatal medicine. To provide relevant data for a Northern Ireland population group, we evaluated mortality and morbidity of extremely low birthweight (ELBW; < 1000 g) infants from a tertiary referral neonatal unit. Seventy-seven ELBW infants were admitted on the first day of life during the period April 1990 to...