Impaired modulation of emotional memory is a feature of several affective disorders, including depression, anxiety and PTSD. AMPA receptor trafficking during the first hours after memory retrieval is crucial in modulation of emotional memory. We unknown targets, when applied via cannulas into the dorsal hippocampus 6 h after memory retrieval, was able to normalize the GluA2 up regulation and th...

Environmental data are spatial, temporal, and often come with many zeros. In this paper, we included space–time random effects in zero-inflated Poisson (ZIP) and ‘hurdle’ models to investigate haulout patterns of harbor seals on glacial ice. The data consisted of counts, for 18 dates on a lattice grid of samples, of harbor seals hauled out on glacial ice in Disenchantment Bay, near Yakutat, Ala...

OBJECTIVE Investigate whether non-daily smokers' (NDS) cigarette price and purchase preferences, recent cessation attempts, and current intentions to quit are associated with the density of the retail cigarette product landscape surrounding their residential address. PARTICIPANTS Cross-sectional assessment of N=904 converted NDS (CNDS). who previously smoked every day, and N=297 native NDS (N...

The Arabidopsis genome encodes ten Homeodomain-Leucine zipper (HD-Zip) II proteins. ARABIDOPSIS THALIANA HOMEOBOX 2 (ATHB2), HOMEOBOX ARABIDOPSIS THALIANA 1 (HAT1), HAT2, HAT3 and ATHB4 are regulated by changes in the red/far red light ratio that induce shade avoidance in most of the angiosperms. Here, we show that progressive loss of HAT3, ATHB4 and ATHB2 activity causes developmental defects ...

MicroRNAs (miRNAs) play critical regulatory roles by acting as sequence specific guide during secondary wall formation in woody and non-woody species. Although thousands of plant miRNAs have been sequenced, there is no comprehensive view of miRNA mediated gene regulatory network to provide profound biological insights into the regulation of xylem development. Herein, we report the involvement o...

Zinc is a component of one-tenth of all human proteins. Its cellular concentration is tightly regulated because its dyshomeostasis has catastrophic health consequences. Two families of zinc transporters control zinc homeostasis in organisms, but there is little information about their specific developmental roles. We show that the ZIP transporter Fear-of-intimacy (Foi) is necessary for the form...

We present a simple system that exploits domain knowledge to improve the segmentation and recognition of handwritten ZIP codes. Specifically, we show that the concept of metaclasses of digits, introduced by Morita et al. [16] for recognition of Brazilian bank check dates, can be extended to ZIP code recognition. We also show that, when this domain knowledge is present, integrated segmentation a...

PURPOSE The aim of this study was to compare the shaping effectiveness rotary nickel-titanium (Profile .04 ISO), ultrasonic (K-Type/Satelec), and stainless-steel hand file (K-file/Maillefer) instrumentation and to assess tubular penetration of 2 gutta percha sealers (AH Plus and Sealite-Ultra) following 4 different final irrigation regimens in primary molar roots. METHODS Distal roots of extr...

~ l Warsaw University, Bialystok Branch, PL 15 48$ -Bi-alystok, Poland DRFMC, Centre d'Etudes Nucleaires de Grenoble, Boite Postale 85X, 880/1 Grenoble, France Continuous Electron Beam Accelerator Facility, Newport News, Uirginia 85'6'06' Gesellschaft fur Schwerionenforschumg Darmstadt, Postfach 1105/1, D 6100 D-armstadt, Germany ~Centre de Spectrometric Nucleaire et de Spectrometric de Masse, ...

Introduction The NYC Department of Health and Mental Hygiene (DOHMH) ED syndromic surveillance system receives data from 95% of all ED visits in NYC totaling 4 million visits each year. The data include residential ZIP code as reported by the patient. ZIP code information has been used by the DOHMH to separate visits into NYC and nonNYC for analysis; and, a closer examination of non-NYC visits ...