A three-component 1,2-aminoarylation of vinyl ethers, enamides, ene-carbamates and thioethers by synergistic photoredox nickel catalysis is reported. 2,2,2-Trifluoroethoxy carbonyl protected α-amino-oxy acids are used as amidyl radical precursors. anti-Markovnikov addition the to alkene Ni-mediated radical/transition metal cross over lead corresponding product. The cascade, which can be conduct...

objective(s) motility plays a major role in pathogenicity of helicobacter pylori, yet there is  scarce data regarding its chemotactic behaviour. the present study was designed to investigate the chemotactic responses of local isolates of h. pylori towards various sugars, amino acids, as well as some other chemical substances. materials and methods chemotaxis was assayed by a modified adler’s me...

addition of potassium cyanide to a mixture of schiff base and lithium perchlorate afforded a-aminonitriles in high yields. addition of potassium cyanide to a methanolic solution of schiff base and phosphoric acid afforded a-aminonitriles. when the reaction mixture was refluxed it gave a-amino acids in high yields.

N-Protected amino acids can be easily converted into chiral α-amino aldehydes in a one-pot reaction by activation with CDI followed by reduction with DIBAL-H. This method delivers Boc-, Cbz- and Fmoc-protected amino aldehydes from proteinogenic amino acids in very good isolated yields and complete stereointegrity.

in lb is research, adsorption of some amino acids and their complenation with manganese (ii) ion on carbonnanotube (mwcnt) by using of four relations langmuir, freundlich. temkin and harkins -jura imitherms wasinvestigated. from this relations. freudlich and temkin relations predict good equilibrium diagram in, isothermcondition. we could compute the theoretical constants by excel software. hy ...

background: addition of amino acids to the culture medium is beneficial for embryonic development in many species. objective: the objective of this study was to investigate the effects of amino acids on the in vitro maturation and embryonic development of the bovine oocyte. materials and methods: bovine ovaries were collected from a local abattoir and brought into laboratory. cumulus-oocyte com...

background: the mesobuthus eupeus scorpion venoms are known to contain α-toxin peptides, many of which interfere with k+ ion channel function. these toxin peptides have important value in  the pharmacology and physiology studies of specific k+ channel of cells. objectives: given the  lack of information of the molecular biology of peptides in the toxin of iranian scorpions, the aim of this stud...

lysozyme is one of the bioactive components of eggs with well known antibacterial potential, widely used in food industry, medicine and pharmaceutics. in this study, the possibility of quail’s egg lysozyme concentration and activity (modified via amino acids dietary supplementation) was investigated. in accordance with lysozyme amino acids profile, four amino acids of: asparagine, arginine, gly...

D-amino acids are valuable building blocks for the synthesis of biologically active compounds and pharmaceuticals. The asymmetric chiral amino from prochiral ketones using stereoselective enzymes is a well-known but far exhausted approach large-scale production. Herein, we investigated pyridoxal-5′-phosphate-dependent acid transaminase Haliscomenobacter hydrossis as potential biocatalyst enzyma...

The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25. Shapes of the diagrams indicate that amino acids polarity and capability for hydrogen bonding have influence on the se...