نتایج جستجو برای: α glucosidase
تعداد نتایج: 169968 فیلتر نتایج به سال:
Glycosidases are the enzymes involved in various biochemical processes related to metabolic disorders and diseases. Therefore, much effort has been focused on searching novel pharmacotherapy for the treatment of these ailments from medicinal plants due to higher safety margins. To pursue these efforts, the present study was performed to evaluate the α-glucosidase inhibitory activities of thirty...
Glycosidases are the enzymes involved in various biochemical processes related to metabolic disorders and diseases. Therefore, much effort has been focused on searching novel pharmacotherapy for the treatment of these ailments from medicinal plants due to higher safety margins. To pursue these efforts, the present study was performed to evaluate the α-glucosidase inhibitory activities of thirty...
α-Glucosidase inhibitors are effective in controlling postprandial hyperglycemia, which play crucial roles the management of type 2 diabetes. Protocatechuic acid (PCA) is one phenolic acids existing not only various plant foods but also as a major microbial metabolite dietary anthocyanins large colon. The present study investigated inhibitory mechanism PCA on α-glucosidase <em...
glycosidases are the enzymes involved in various biochemical processes related to metabolic disorders and diseases. therefore, much effort has been focused on searching novel pharmacotherapy for the treatment of these ailments from medicinal plants due to higher safety margins. to pursue these efforts, the present study was performed to evaluate the α-glucosidase inhibitory activities of thirty...
The antioxidant, anti-α-glucosidase and anticholinesterase activity of the leaves and rhizomatous extract of Bergenia cordifolia were investigated. The rhizomes extract that showed a higher degree of 1,1-diphenyl-2-picrylhydrazyl radical scavenging and anti-α-glucosidase activity than reference compounds (rutin and acarbose respectively) were subjected to phytochemical analysis. The study revea...
The present study was to evaluate the anti-diabetic activity of the aqueous extract of Actinidia kolomikta root against baker's yeast α-glucosidase and rat intestinal α-glucosidase. As a result, the aqueous extract of Actinidia kolomikta root exhibited excellent baker's yeast α-glucosidase inhibitory activity which was better than acarbose. It also showed rat intestinal α-glucosidase inhibitory...
BACKGROUND α-glucosidase inhibitors regulate postprandial hyperglycemia (PPHG) by impeding the rate of carbohydrate digestion in the small intestine and thereby hampering the diet associated acute glucose excursion. PPHG is a major risk factor for diabetic vascular complications leading to disabilities and mortality in diabetics. Cinnamomum zeylanicum, a spice, has been used in traditional medi...
The potent α-glucosidase inhibitor (compound I) was isolated from coffee brews by the activity-based fractionation and identified as a β-carboline alkaloid norharman (9H-pyrido[ 3.4-b]indole) on the basis of mass spectroscopy and nuclear magnetic resonance spectra ((1)H NMR, (13)C NMR, and COSY). The norharman showed a potent inhibition against α-glucosidase enzyme in a concentration dependent ...
A series of 3-styrylchromone derivatives (4-20) were synthesized and the structure-activity relationships for α-glucosidase inhibition and antioxidant activities were analyzed. Among the synthesized compounds, compounds 15 and 20, which contain a catechol moiety, showed both potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (15: EC₅₀=17 µM; 20: EC₅₀=23 µM) and α-gluco...
We screened for α-glucosidase inhibitors from 12 traditional medicinal plants used for the treatment of diabetes. Potent α-glucosidase inhibitory activity was found in aqueous extract of Psidium guajava leaves and Syzygium cumini Linn seed extract. Active principles inhibiting α-glucosidase were isolated and identified as apigenin 7O-glucoside in the S.cumini Linn seed extract and Dihydro-3,3’,...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید