نتایج جستجو برای: β1

تعداد نتایج: 13587  

ژورنال: کومش 2015

  سابقه و هدف: یکی از علل بروز سقط‌های مکرر، دخالت عوامل ایمونولوژیک در این نوع سقط می‌باشد. داروی سیکلوسپورین، موجب کاهش سقط در مدل حیوانی CBA/j×DBA/2 می‌گردد. آنتی‌بادی‌های نا‌متقارن و TGF-β از عوامل مهم تعیین‌کننده سرنوشت حاملگی است. مطالعه حاضر به منظور بررسی تاثیر سایکلوسپورین بر میزان این نوع آنتی‌بادی‌ها و سیتوکاین TGF-β1 سرمی، در مدل حیوانی سقط، انجام گرفت.   مواد و روش ‌ ها: موش‌های CB...

Journal: :The Journal of Urology 2021

You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology Pharmacology (MP08)1 Sep 2021MP08-13 MICRORNA-29a REGULATES TGF-β1-INDUCED EXPRESSION OF COLLAGEN 1a1 IN HUMAN UROTHELIAL CELLS Zunyi Wang, Jianghui Hou, and Dale Bjorling WangZunyi Wang More articles by this author , HouJianghui Hou BjorlingDale View All Author Informationhttps://doi.org/10.1097/JU.0000000000001981.13About...

Maryam Ghasemi, Saeid Abediankenari, Young-June Kim,

Background: During antigen capture and processing, mature dendritic cells (DC) express large amounts of peptide-MHC complexes and accessory molecules on their surface. DC are antigen-presenting cells that have an important role in tolerance and autoimmunity. The transforming growth factor-beta1 (TGF-β1) cytokine has a regulatory role on the immune and non-immune cells. The aim of this study is ...

Journal: :Applied Mathematics Letters 2021

We discuss the Cauchy problem for a parabolic attraction–repulsion chemotaxis system: ∂tu=Δu−∇⋅(β1u∇v1)+∇⋅(β2u∇v2),t>0,x∈R2,∂tvj=Δvj−λjvj+u,t>0,x∈R2(j=1,2),u(0,x)=u0(x),vj(0,x)=vj0(x),x∈R2(j=1,2)with positive constants βj,λj>0 (j=1,2) satisfying β1>β2. In our companion paper, authors proved existence of global-in-time solutions any initial data with (β1−β2)∫R2u0dx<8π. this we prove that every s...

Journal: :Applied sciences 2021

In our previous study, 4-hexylresorcinol (4HR) increased the expression level of vascular endothelial growth factor in human umbilical vein cells (HUVECs) via transforming factor-β1 (TGF-β1)-mediated pathway. Endoplasmic reticulum (ER) and mitochondrial stress is a positive regulator cellular differentiation. As TGF-β1 master for differentiation, 4HR treatment may increase ER stress. this HUVEC...

حبیبیان, معصومه, صبحی, ناصرالدین,

زمینه و هدف : پیری با آنژیوژنز آسیب‌دیده، گلومرواسکلروز و افزایش ابتلا به آسیب نفروتوکسیک همراه است. این مطالعه به منظور تعیین اثر مستقل و ترکیبی تمرین هوازی شنا و عصاره سیر بر سطح کلیوی عامل رشد اندوتلیال عروقی (VEGF) و عامل رشد تبدیل بتا -1 (TGF-β1) در موش‌های صحرایی پیر انجام شد. روش بررسی : در این مطالعه تجربی 35 سر موش صحرایی نر پیر (50-48 هفته‌ای) از نژاد ویستار به صورت تصادفی در گروه‌های...

Behzad Khansarinejad, Mandana Beigi Boroujeni, Mehri Fayazi, Mojdeh Salehnia,

Background: Integrins are heterodimeric glycoprotein receptors that regulate the interaction of cells with extracellular matrix and may have a critical role in implantation. The aim of this study was to investigate the effect of ovulation induction on the expression of α4, αv, β1, and β3 integrins in mouse blastocyst at the time of implantation. Methods: The ovarian stimulated and non-stimulate...

Background and Objectives: Curcumin and exercise training are suggested to improve hepatic disorders. The aim of this study was to investigate effects of two weeks of swimming training and curcumin supplementation on platelet-derived growth factor (PDGF-BB) and transforming growth factor beta 1 (TGF-β1) gene expressions following ethanol consumption in Wistar male rats. Materials and Methods: ...

Journal: : 2022

Acute myeloid leukemia is a genetically heterogeneous clonal disease defined by the accumulation of immature cells in bone marrow and blood. The aim this study to evaluate CD33, CD11b, HLA-DR expression Iraqi AML patients its role evasion malignant from immune system. This was conducted on 60 with 20 healthy individuals as control group CD33 CD11b using flow-cytometry peripheral blood, Interfer...

Masoumeh Habibian Mohammad Reza Saghafi Parvin Farzanegi

Background & Aims: Numerous studies have reported the renoprotective effects of exercise in both human and animal models of diabetic nephropathy. However, detailed mechanism of action by which exercise has a favorable influence on renal fibrogenic factors is not yet fully understood. Therefore, the aim of this study was to assess the effect of swimming exercise on the activity ...

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