BACKGROUND The relevance of healthcare provider cultural competency to the achievement of goals for reduction in extant health disparities has been demonstrated; however, there are deficits with regard to cultural competency measurement. OBJECTIVES To examine the test-retest reliability of the cultural competence assessment instrument (CCA) among hospice providers, and to examine the reliabil...

Kernel canonical correlation analysis (CCA) is a nonlinear extension of CCA, which aims at extracting information shared by two random variables. In this paper, a new notion of conditional kernel CCA is introduced. Conditional kernel CCA aims at analyzing the effect of variable Z to the dependence between X and Y . Rates of convergence of an empirical normalized conditional cross-covariance ope...

BACKGROUND An increased leukocyte count is an independent risk factor for cardiovascular events, but the association between leukocyte subtype counts and carotid atherosclerosis in patients with diabetes has not been determined. We therefore investigated the correlation between leukocyte subtype counts and intima-media thickness of the common carotid artery (CCA-IMT) in subjects with type 2 dia...

Whether it is possible to construct a chosen ciphertext secure (CCA secure) public key encryption (PKE) scheme only from a chosen plaintext secure (CPA secure) one is a fundamental open problem, and the best known positive results regarding this problem are the constructions of so-called bounded CCA secure schemes. Since we can achieve the best possible security in the bounded CCA security noti...

AIMS To investigate the specific expression of insulin-like growth factor binding protein-1 (IGFBP-1) in ovarian clear cell adenocarcinoma (CCA). METHODS AND RESULTS Immunohistochemistry and in situ hybridization for IGFBP-1 were performed in normal endometrium, placenta, and 100 surgically resected cases of ovarian cancer including 31 CCAs and 69 non-CCAs. Immunohistochemistry for hepatocyte...

Removal of predators can have strong indirect effects on primary producers through trophic cascades. Crustose coralline algae (CCA) are major primary producers worldwide that may be influenced by predator removal through changes in grazer composition and biomass. CCA have been most widely studied in Caribbean and temperate reefs, where cover increases with increasing grazer biomass due to remov...

Transcription in eukaryotes produces a number of long noncoding RNAs (lncRNAs). Two of these, MALAT1 and Menβ, generate a tRNA-like small RNA in addition to the mature lncRNA. The stability of these tRNA-like small RNAs and bona fide tRNAs is monitored by the CCA-adding enzyme. Whereas CCA is added to stable tRNAs and tRNA-like transcripts, a second CCA repeat is added to certain unstable trans...

The Common Component Architecture (CCA) provides a means for software developers to manage the complexity of large-scale scientific simulations and to move toward a plug-and-play environment for high-performance computing. In the scientific computing context, component models also promote collaboration using independently developed software, thereby allowing particular individuals or groups to ...

Canonical correlation analysis (CCA) is a classical tool in statistical analysis to find the projections that maximize the correlation between two data sets. In this work we propose a generalization of CCA to several data sets, which is shown to be equivalent to the classical maximum variance (MAXVAR) generalization proposed by Kettenring. The reformulation of this generalization as a set of co...

Methionine aminopeptidase-2 (MetAP2) is over-expressed in several cancers, including the cholangiocarcinoma (CCA). We reported previously suppressive effects of fumagillin, a MetAP2 inhibitor, on growth of CCA cell lines. In the present study, we evaluated the anti-proliferative and anti-invasive activities of TNP-470, a fumagillin analogue with higher MetAP2 inhibitory activity, on CCA cell li...