Background T-cell receptor (TCR) and B-cell (BCR) repertoire profiling holds great potential for understanding disease mechanisms the development of new therapeutics in infectious diseases, autoimmunity immuno-oncology. However, this could be greatly improved by combining information about clonotypes with immuno-phenotypes T B cells. Methods To facilitate these studies, we developed a novel tec...

SNR0540-69 is a supernova remnant in the LMC, harbouring a young (τ ∼ 1600 yrs) radio/optical/X-ray pulsar (P=50 ms). Ground based Hα imaging of the region has shown a unique spiral-like structure centered around the pulsar. In narrow band HST imaging, the feature seems resolved in a ring-like structure, probably ejected by the progenitor star in a pre-supernova phase (≥ 10 yrs ago).

Thermal denaturation of protonated polynucleotides is accompanied by a change in protonation [l-5] . The thermal transition at a given pH can thus be directly related to the pk’ of the proton-induced structural transition at a given temperature. For poly (A’).poly (A+) a strict relationship has been shown to hold over a large range of conditions [4-61. In fig. 1 the results in the literature an...

In this study, the cytogenetic effects of a sulphonylurea group herbicide Logran (effective substance; Triasulfuron) were investigated in human peripheral blood lymphocyte culture. The cultures were treated with 2, 4, 8, 16, 32, 64, 128, and 256 mg/ml concentrations of Logran for 24 and 48 h. This compound increased chromosome aberrations (CA) in human lymphocyte culture. Logran decreased Mitot...

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