Dominant optic atrophy (DOA) is characterized by retinal ganglion cell degeneration leading to optic neuropathy. A subset of DOA is caused by mutations in the OPA1 gene, encoding for a dynamin-related GTPase required for mitochondrial fusion. The functional consequences of OPA1 mutations in DOA patients are still poorly understood. This study investigated the effect of five different OPA1 patho...

This paper presents a tool for the analysis, and simulation of direction-of-arrival (DOA) estimation in wireless mobile communication systems over the fading channel. It reviews two methods of Direction of arrival (DOA) estimation algorithm. The standard Multiple Signal Classification (MUSIC) can be obtained from the subspace based methods. In improved MUSIC procedure called Cyclic MUSIC, it ca...

Each element in the conformal array has a different pattern, which leads to the performance deterioration of the conventional high resolution direction-of-arrival (DOA) algorithms. In this paper, a joint frequency and two-dimension DOA (2D-DOA) estimation algorithm for conformal array are proposed. The delay correlation function is used to suppress noise. Both spatial and time sampling are util...

A computationally efficient method for nominal 2-D (azimuth and elevation) direction-of-arrival (DOA) estimation of coherently distributed source impinging on the far field is presented. Since the coherently distributed source is characterized by four parameters, the nominal azimuth DOA, angular spread of the nominal azimuth DOA, the nominal elevation DOA, and angular spread of the nominal elev...

In this paper, we present a novel DOA estimation method for human speech using subband weighting. Existing DOA estimation methods still can not perform quite reliably in low SNR condition. To improve the robustness of DOA estimator in noisy environment, we propose a novel DOA estimation approach. Firstly, the speech signal of each channel is passed through a Gammatone filterbank to obtain a set...

Antenna arrays are likely to be an important feature of future mobile communication systems. With an antenna array, mobile users can be separated by a spatial filtering procedure allowing several users on the same carrier frequency. The uplink part (mobile to base) not only can, but is better solved without using any spatial knowledge in terms of direction of arrival (DOA). However, DOA estimat...

Complacency refers to a type of automation use expressed as insufficient monitoring and verification of automated functions. Previous studies have attempted to identify the age-related factors that influence complacency during interaction with automation. However, little is known about the role of age-related differences in working memory capacity and its connection to complacent behaviors. The...

We investigated the problem of automatic depth of anesthesia (DOA) estimation from electroencephalogram (EEG) recordings. We employed Time Encoded Signal Processing And Recognition (TESPAR), a time-domain signal processing technique, in combination with multi-layer perceptrons to identify DOA levels. The presented system learns to discriminate between five DOA classes assessed by human experts ...

OF THE DISSERTATION Underwater Direction-of-Arrival Finding: Maximum Likelihood Estimation and Performance Analysis by Tao Li Doctor of Philosophy in Electrical Engineering Washington University in St. Louis, May 2012 Research Advisor: Dr. Arye Nehorai In this dissertation, we consider the problems of direction-of-arrival (DOA) finding using acoustic sensor arrays in underwater scenarios, and d...

The purpose of this study was to assess changes in exit velocity (EV) of Brahman calves from 21 d of age (DOA) to 56 d postweaning (231.30 ± 1.23 DOA). Spring-born calves (n = 308) from 2006 to 2008 were sired by 18 bulls. Exit velocity (m/s) was determined as the rate of speed of a calf traversing 1.83 m after being released from a working chute. Temperament score was determined as the average...