Alcohol oxidase (AO) is a homo-octameric flavoenzyme which catalyzes methanol oxidation in methylotrophic yeasts. AO protein is synthesized in the cytosol and subsequently sorted to peroxisomes where the active enzyme is formed. To gain further insight in the molecular mechanisms involved in AO activation, we studied spectroscopically native AO from Hansenula polymorpha and Pichia pastoris and ...

BACKGROUND The relationship between abdominal obesity (AO) and mortality in peritoneal dialysis (PD) patients is controversial. METHODS The prevalence of AO in 84 PD patients was assessed in a cross-section manner and followed up for 9 years at a single center. AO was defined as a waist circumference (WC) of more than 90 cm in males or more than 80 cm in females. The patients were classified ...

Enhanced indexing is a hybrid fund management style that presents elements of both the active and the passive investment styles. This work presents the basic principles of enhanced indexing fund management, and proposes a methodology to generate the set of its e cient portfolios. Important operational details for practitioners are addressed, such as choosing an appropriate market risk measure, ...

BACKGROUND The ratio of the diameter of the main pulmonary artery (mPA) to the diameter of the aorta (Ao) on chest computed tomography is associated with diverse clinical conditions. Herein, we determined the functional and prognostic implications of the mPA/Ao ratio in Korean chronic obstructive pulmonary disease (COPD) patients. METHODS The study population comprised 226 chronic obstructive...

AIM We undertook studies to determine the lethal dose 50 (LD50) of acridine orange (AO) using mice in order to confirm the safety of intravenous administration of AO. MATERIALS AND METHODS We used 40 mice and AO was administered once intravenously. General behavior and mortality were continuously observed for 14 days. At the end of the experiment, all animals were sacrificed for subsequent st...

A volumetric data set is a collection of data in which each data has an associated location in the three-dimensional space. In this work we review the wavelets theory and discuss the application of this technique to the visualization of volumetric data. We show the main algorithms, and discuss some implementation issues.

O problema da ordenação é sem dúvida um dos mais estudados na Ciência da Computação. No escopo da computação moderna, depois de mais de 60 anos de estudos, ainda existem muitas pesquisas que objetivam o desenvolvimento de algoritmos que solucionem uma ordenação mais rápida ou com menos recursos comparados a outros algoritmos já conhecidos. Há vários tipos de algoritmos de ordenação, alguns mais...

Action observation (AO), observing another individual perform an action, has been implicated in several higher cognitive processes including forming basic motor memories. Previous work has shown that physical practice (PP) results in cortical motor representational changes, referred to as use-dependent plasticity (UDP), and that AO combined with PP potentiates UDP in both healthy adults and str...

Purpose We compared cone density measurements derived from the center of gaze-directed single images with reconstructed wide-field montages using the rtx1 adaptive optics (AO) retinal camera. Methods A total of 29 eyes from 29 healthy subjects were imaged with the rtx1 camera. Of 20 overlapping AO images acquired, 12 (at 3.2°, 5°, and 7°) were used for calculating gaze-directed cone densities...