Previously, we detected, by monoclonal antibody, three Moloney mu rine sarcoma virus (Mo-MSV)-activated intraccllular transformationassociated proteins (TAP), (P66, P63, and P60) in several Mo-MSVtransformed rat cell lines (Gian et al., Biochem. Biophys. Res. Commun., 134:1223-1230, 1986) and found the release of TAP into the extracel lular medium with a change from three intraccllular polypept...

The aim of this study was to examine the role of nitric oxide (NO) in the control of cardiac metabolism at 60 days of pregnancy (P60) in the dog. There was a basal increase in diastolic coronary blood flow during pregnancy and a statistically significant increase in cardiac output (55 +/- 4%) and in cardiac NOx production (44 +/- 4 to 59 +/- 3 nmol/min, P < 0.05). Immunohistochemistry of the le...

Inflammation, neurodegeneration and microvascular irregularities are included in the spectrum of defects associated with diabetic retinopathy. Here, we evaluated intraocular deliverability features of two pigment epithelium-derived factor (PEDF) derivatives given as eye drops and their efficacy in modulating diabetes-induced retinal complications. The antiangiogenic PEDF60-77 (P60) and neuropro...

In the current report, we investigated the possibility of a cross-talk between receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor alpha (TNF-alpha) using macrophage cell lines derived from wild-type mice and from mice with genetic deletion of the type 1 TNF receptor (p60(-/-)), the type 2 TNF receptor (p80(-/-)), or both receptors (p60(-/-)p80(-/-)). Deletion of TNF recept...

ABSTRAKPeningkatan kualitas kecambah dapat dibantu dengan seed priming, seperti perendaman dalam larutan pupuk organik cair. Penelitian bertujuan untuk mengetahui: pengaruh berbagai bahan dan konsentrasi priming terhadap perkecambahan biji aren (Arenga pinnata (Wurmb.) Merr.), waktu aren, interaksi antara pada aren. dilaksanakan di Dusun 2 Desa Pasir Kulon Kecamatan Karanglewas Kabupaten Banyum...

&lt;p&gt;&lt;strong&gt;Background.&lt;/strong&gt; The study of space allowance (m&lt;sup&gt;2&lt;/sup&gt;) per animal is important, due in current production systems different group sizes are used throughout the year, without knowing their possible effects on daily weight gain and growth during fattening period. &lt;strong&gt;Objective.&lt;/strong&gt; effect hair lambs raised-slatted floor cage...

Cyclophilin D (CypD), a regulator of the mitochondrial membrane permeability transition pore (PTP), enhances Ca(2+)-induced mitochondrial permeabilization and cell death in the brain. However, the role of CypD in hypoxic-ischemic (HI) brain injury at different developmental ages is unknown. At postnatal day (P) 9 or P60, littermates of CypD-deficient [knock-out (KO)], wild-type (WT), and hetero...

The neural mechanisms by which maternal infections increase the risk for schizophrenia are poorly understood; however, animal models using maternal administration of immune activators suggest a role for cytokine imbalance in maternal/fetal compartments. As cytokines can potentially affect multiple aspects of neuronal development and the neuropathology of schizophrenia is believed to involve sub...