insulin-loaded biodegradable chitosan nanoparticle was prepared by the polyelec-trolyte complex formation method. the prepared nanoparticles were in the size of 110 nm and had high entrapment (91.0%) capacity. the transdermal nanoinsulin was characterized by in vivo hypoglycemic effects. plasma glucose was decreased to the range of 80.34 to 96.74 mg/dl, and insulin levels were increased to the ...

background: based on literature, in vitro cholesterol removal of lactic acid bacteria has been accounted for their in vivo cholesterol reduction. but recently, it has been proposed that such in vitro characteristic may not be directly relevant to their in vivo activity. the objective of this study was to find how much in vitro cholesterol reducing potential of lactobacillus plantarum a7 (la7), ...

objective(s):  the field of nanotechnology is rapidly expanding .the development quantum dots quantum dot (qds), show great promise for treatment and diagnosis of cancer and targeted drug delivery little data on the toxicity of qds, especially for in vivo applications, are available. as a result, concerns exist over their toxicity for in vivo applications. then, cytotoxic effects of cadmium sel...

abstract background: in vivo measurements of applied dose during radiotherapy treatment, is important to ensure accurate dose delivery to patients. uncertainty in dose delivery should fall within ±5% of the prescribed dose as recommended by icru. assessment of dose for radiotherapy applications performed with various types of detectors. in this study, semiconductor diodes were used which have s...

background: delivering the maximum dose to tumor while achieving the minimum dose delivery to normal tissue; is the most important goal in external radiotherapy. diode in vivo dosimetry is widely considered to be an important tool for quality improvement of patient care in external radiotherapy. uncertainty in dose delivery should fall within 5% of the prescribed dose as recommended by internat...