Polymicrogyria (PMG) is a widespread cortical malformation frequently associated with seizures and EEG spikes. Its epileptogenicity is poorly understood. Nine patients with simultaneous EEG and fMRI were studied to assess the blood oxygenation level-dependent response to spikes. Sixteen of 18 studies showed responses, with maximum activation involving the lesion in 61.5%, but often limited to a...

BACKGROUND A diaphragmatic phonomyogram (PMG) evoked by maximal phrenic nerve stimulation at end expiratory lung volume (FRC) has been previously described as a good index of changes in diaphragmatic contractility with fatigue. A study was undertaken to assess whether this conclusion could be extended to different lung volumes. METHODS Diaphragmatic compound motor action potentials (CMAPs) we...

We report the preparation and characteristics of a novel micellar aggregate of an amphiphilic diblock copolymer, poly(methylglutamate) (PMG)-poly(ethyleneglycol) (PEG), whose terminus was modified by lactose lactone (LA). Due to the terminal LA moiety, this aggregate could be specifically recognized by RCA120 lectin. PMG-PEG-LA was synthesized by polymerizing the N-carboxy anhydride of L-glutam...

The effects of the expression of a small heat shock protein (shsp) gene from Streptococcus thermophilus on stress resistance in Lactococcus lactis under different environmental stresses were investigated in this study. pMG36e-shsp, an expression vector, was first constructed by inserting a shsp open reading frame (ORF) cloned from S. thermophilus strain St-QC into pMG36e. Then, a food-grade exp...

In this paper, an efficient and convenient Fe3O4/PMG/IDA-Ni2+ nanoparticles that applied to purify and immobilize his-tagged β-glucosidase was synthesized, in which, Fe3O4/PMG (poly (N, N'-methylenebisacrylamide-co-glycidyl methacrylate) core/shell microspheres were synthesized firstly using distillation-precipitation polymerization, then iminodiacetic acid (IDA) was used to open epoxy rings on...

A small scale wind energy conversion system has tremendous diversity of use and operating conditions, and consequently is evolving rapidly along with the large scale wind energy conversion system for generation of electricity in either stand-alone or grid connected applications. In recent years, the grid connected small wind turbine industry is primarily dominated by the Permanent Magnet Genera...

Developmental cortical malformations are common in patients with intractable epilepsy; however, mechanisms contributing to this epileptogenesis are currently poorly understood. We previously characterized hyperexcitability in a rat model that mimics the histopathology of human 4-layered microgyria. Here we examined inhibitory and excitatory postsynaptic currents in this model to identify functi...

Distributed computing has been considered for decades as a promising way of speeding up software execution, resulting in a valuable collection of safe and efficient concurrent algorithms. With the pervasion of multi-core processors, parallelization has moved to the center of attention with new challenges, especially regarding scalability to tens or even hundreds of parallel cores. In this paper...

Diabetes is a significant and growing concern, with over 246 million people around the world living with the disease and another 308 million with impaired glucose tolerance. Depending on the resources of different nations, intervention has generally focused on optimizing overall glycaemic control as assessed by glycated haemoglobin (HbA(1c)) and fasting plasma glucose (FPG) values. Nevertheless...

superconducting materials are capable of trapping extremely high magnetic fields. this property and meissner effect of superconductors causes a levitation force between bulk superconductors and a permanent magnet (pm). this levitation force has possible industrial applications such as permanent magnet guideways (pmg). because of the high price of permanent magnets, the optimization of pmg desig...