Inhibition of prostaglandin E(2) (PGE(2)) production in lipopolysaccharide-stimulated RAW264.7 mouse macrophage cells was assessed with an enzyme immunoassay following treatments with Echinacea extracts or synthesized alkamides. Results indicated that ethanol extracts diluted in media to a concentration of 15 microg/mL from E. angustifolia, E. pallida, E. simulata, and E. sanguinea significantl...

Alkamides are one of the most important constituents of lipophilic extracts of Echinacea angustifolia roots. These compounds play an important role in the versatile pharmacological actions of this plant. The present study aimed to compare the concentrations of isomeric dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (DTAI) in brain and periepididymal fat tissues and blood plasma of rats. T...

Phytochemical investigation of the leaf surface exudate of Dodonaea angustifolia L.f. yielded two new neo-clerodane diterpenes, neo-clerodan-3,13-dien-16,15:18,19-diolide (mkapwanin) and 15-methoxyneo-clerodan-3,13-dien-16,15:18,19-diolide (15-methoxymkapwanin). In addition, ten known compounds were identified. The structures were determined on the basis of spectroscopic evidence. This addition...

Two glycosides were isolated from the n-Butanol soluble portion of the ethanolic portion of the stem and leaves part of stachytarpheta angustifolia. Their structures were elucidated as Iridoid glycoside (1) and a caffeic glycoside ester named as –β(3 1 , 4 1 dihydroxyphenyl)–ethyl-O-α-L-rhamnopyranosyl-(1-3)-β-D-(4-O-Caffeoyl) glucopyranoside (2) by spectroscopic Method.

Cucurbitacin F and the cyanogenetic compounds prunasin were isolated and identified from the seeds of Kageneckia angustifolia.

Near-infrared (NIR) reflectance spectroscopy was used to develop a fast identification method for Echinacea purpurea dried milled roots. Method development was carried out using a PLS (partial least-squares) algorithm and pretreatment options. The aim of this qualitative analysis was to confirm the identity of E. purpurea and to detect the presence of fraud, i.e., samples adulterated or substit...

Pollen limitation of plant reproduction occurs in many plant species, particularly those in fragmented habitat; however, causes of pollen limitation are often unknown. We investigated the relationship between pollen limitation and pollinator visitation in the purple coneflower, Echinacea angustifolia (Asteraceae), which grows in the extremely fragmented tall grass prairie of North America. Prev...