Nigella sativa, known as black seed, has analgesic, anti-inflammatory, antioxidant and anticancer effects. It has been shown to reduce the development of kidney failure when given prior to the use of nephrotoxic drugs particularly due to its antioxidant action. However, as far as the authors could ascertain, there is no human study in literature showing these effects. Here we present a case of ...

background: the task force on plants for fertility regulation in men continued with its program to identify novel prototypes in plants alleged to have fertility regulating properties. nigella sativa   objective: to evaluated the role of alcoholic extract of nigella sativa on fertility potential, pituitary-testicular axis hormones and testosterone in male rats.   materials and methods: 24 male r...

Synthesis of silver nanoparticles using seeds of Nigella sativa as reducing agent was evaluated in this study. Homogenized extract of N. sativa exposed to sunlight gave a better synthesis of nanoparticles when compared to other methods. Antibacterial activity of nanoparticles was studied against urinary tract infection (UTI) causing bacteria by disc diffusion method. Further, the silver nanopar...

Nigella sativa (NS) has been shown to have antioxidant, anti-inflammatory and antiulcer activities in different conditions. The present work was done to investigate the possible effects of Nigella sativa aqueous extracts (NS) on gastric acid secretion in isolated rat stomach. Gastric acid secretion was measured in the isolated rat stomach preparation. The results obtained in vitro experiments s...

Objectives: Nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. Numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. The aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of Nigella sativa oil in patients with rheumatoid ar...

The fixed oil of black cumin seeds, Nigella sativa L. (NSO), has shown considerable antioxidant and anti-inflammatory activities. Chronic cerebral hypoperfusion has been linked to neurodegenerative disorders including Alzheimer's disease (AD) and its subsequent cognitive impairment in which oxidative stress and neuroinflammation are the principal culprits. Cerebrovascular hypoperfusion was expe...

Background: Premenstrual Syndrome (PMS) is a common problem in women. Nigella sativa has been suggested for its anti-inflammation and analgesic effects. This study was conducted to evaluate the effect of Nigella sativa oil on PMS. Methods: This double-blind clinical trial was conducted on 124 female students within the age range of 18-25 years living in the dormitories of Sabzevar University of...

Objective (s): Titanium dioxide nanoparticles (TiO2 NPs) have been recognized as biologically inert material and have been used in a multitude of applications. Nevertheless, the negative impact on the human health is not yet well understood. Aim of the work: The study attempted to evaluate the epigenetic changes of the genome, in the form of DNA methylation in liver tissue samples, resulting fr...