A Purpose: A review of the Activator Methods chiropractic technique (AMCT) and Activator adjusting instrument (AAI) is presented. History and development of the technique and its evidence basis and safety issues are discussed. Method: Activator history and associated body of research literature on both the technique and the instrument are critically reviewed. Included are basic science research...

While attachment research has demonstrated that parents' internal working models of attachment relationships tend to be transmitted to their children, affecting children's developmental trajectories, this study specifically examines associations between adult attachment status and observable parent, child, and dyadic behaviors among children with autism and associated neurodevelopmental disorde...

The current study examined the intergenerational transmission of role reversal within a developmental psychopathology framework. Role reversal is a relationship disturbance in which a parent looks to a child to meet the parent's need for comfort, parenting, intimacy, or play, and the child attempts to meet these needs. In a normative sample, n=138, fathers and mothers reported on childhood role...

The inclusion of animals into interventions for children with autism spectrum disorder (ASD) is a growing practice known as animal-assisted intervention (AAI). The choice of the animal to include in an intervention is often solely up to the interventionist and depends on their experience, subjective judgment, and ease of access to different animals. For individuals with ASD who are non-verbal a...

BACKGROUND At present there are no measures to identify the cognitive processes and behaviours that might mediate the outcome of treatment in people with Body Dysmorphic Disorder (BDD). AIMS To develop and validate a process measure that can be used to assess the progress of patients throughout therapy and in research for BDD. METHOD The psychometric properties of the Appearance Anxiety Inv...

Chronic schistosome infections protect against allergic airway inflammation (AAI) via the induction of IL-10-producing splenic regulatory B (Breg) cells. Previous experiments have demonstrated that schistosome-induced pulmonary B cells can also reduce AAI, but act independently of IL-10. We have now further characterized the phenotype and inhibitory activity of these protective pulmonary B cell...

PURPOSE Apoptosis is an important mechanism regulating survival of acute myeloid leukemia cells. The apoptosis-related protein profile at diagnosis is important for achieving complete remission thereby affecting survival variables such as disease-free survival (DFS) and overall survival (OS).To investigate the role of the apoptosis protein profile in further response to therapy and outgrowth of...

BACKGROUND The TAS2R38 gene is widely responsible for the well-known bimodal response to a family of bitter chemicals which includes 6-n-propylthiouracial (PROP). There are two common haplotypes of this gene, the recessive AVI and the dominant PAV, both of which are well studied. Conversely, the role of rare TAS2R38 haplotypes on bitter taste sensitivity has been notoriously difficult to study ...

BACKGROUND The purpose of this study was to assess simultaneous right and left atrial pacing as prophylaxis for postoperative atrial fibrillation. METHODS AND RESULTS In a double-blind, randomized fashion, 118 patients who underwent open heart surgery were assigned to right atrial pacing at 45 bpm (RA-AAI; n=39), right atrial triggered pacing at a rate of >/=85 bpm (RA-AAT; n=38), or simultan...