The development of novel, systemically administered radionuclide therapies (such as radioimmunotherapy) relies on the ability to predict dose-limiting toxicity to normal tissue. Where the kidney is the principal route of excretion of the radionuclide preparation and/or breakdown of products, nephrotoxicity may be the dose-limiting factor. Until recently, conventional (MIRD) dosimetry assumed th...

The article presents the distribution coefficient (Kd) values of 137Cs and 90Sr tracer radionuclides in solutions sodium calcium salts for a wide range commercially available inorganic sorbents: natural synthetic aluminosilicates, manganese, titanium zirconium oxyhydrates, phosphates, titanosilicates alkali metals, ferrocyanides transition metals. results were obtained using standard technique ...

An assessment was made of the in situ bioaccumulation of 13 polycyclic aromatic hydrocarbons (PAHs) in freshwater isopods in relation to their partitioning between sediments, particulate matter (>0.7 µm), and dissolved phases in eight different water systems of The Netherlands. Large differences in total (Gamma PAHs) concentrations and in relative abundance of individual PAHs were observed betw...

We examined the distribution of the 34-kilodalton (34-kD) tyrosine kinase substrate in tissues of adult and embryonic chicken using both a mouse monoclonal antibody and a rabbit polyclonal antibody raised against the affinity purified 34 kD protein. We analyzed the localization by immunoblotting of tissue extracts, by immunofluorescence staining of frozen tissue sections, and by staining sectio...

Although Kawasaki disease (KD), which was first reported in the 1960s, is assumed to be infectious, its aetiological agent(s) remains unknown. We compared the geographical distribution of the force of infection and the super-annual periodicity of KD and seven other paediatric infectious diseases in Japan. The geographical distribution of the force of infection, which was estimated as the invers...