Social network sites (SNS) have simplified and amplified social interaction between online users. The unique hedonic-oriented features provide experiential motives for SNS users. Although SNS is growing popularity, a number of questions remain to be addressed concerning the usage of SNS: What are experiential motives for SNS users? What is the relationship between flow experiences and behaviora...

Young adolescents are quickly becoming avid users of social networking sites (SNSs); however, little is known regarding how they use these sites. The goal of the present study was to examine the extent to which young adolescents use SNSs, with whom they connect via these sites, and whether SNS use disrupts daily functioning. Among 268 middle-school students surveyed, 63% reported having their o...

Wireless Sensor Networks (WSNs) consist of large number of small sensor nodes (SNs) with sensing, computation, and wireless communications capabilities. The SNs are tightly constrained in terms of energy, bandwidth, storage, computation and transmission ranges. Power is the most critical of all of them. Thus, a keen care needs to be taken in order to provide energy efficiency while developing a...

The results of a series of human and animal studies that were conducted in an effort to better understand autonomic nervous system influences on female sexual arousal are presented. The effects of sympathetic nervous system (SNS) activation on self-report and vaginal photoplethysmographic measures of sexual arousal were examined in 4 studies using intense acute exercise, and in 1 study using ep...

The CDK inhibitor SNS-032 had previously exerted promising anti-neuroblastoma activity via CDK7 and 9 inhibition. ABCB1 expression was identified as major determinant of SNS-032 resistance. Here, we investigated the role of ABCB1 in acquired SNS-032 resistance. In contrast to ABCB1-expressing UKF-NB-3 sub-lines resistant to other ABCB1 substrates, SNS-032-adapted UKF-NB-3 (UKF-NB-3rSNS- 032300n...

Mono- and dicationic divalent palladium complexes having 2,6-bis(N-heteroarylsulfanylmethyl)pyridine ligands (NSNSN ligands) were synthesized and characterized. The NSNSN ligands were fixed in a rac-SNS tridentate coordination mode in the solid state, while the equilibria among meso-SNS, rac-SNS, and NNN isomers were observed in solution. The equilibrium between the SNS and NNN isomers could be...

Inspired by the increasing popularity of advertising on social media, and especially on social network sites (SNS), the aim of this study was to give insight into the effectiveness of SNS advertising. The first experimental study compares consumer responses to advertising on SNS and TV and demonstrates that while TV campaigns are evaluated more positively, SNS campaigns result in more favourabl...

BACKGROUND Acute myeloid leukemia (AML) is a heterogeneous disorder with aberrant regulation of a variety of signal pathways. Therefore, simultaneous targeting of two or even more deregulated signal transduction pathways is needed to overcome drug resistance. Previously, it was reported that SNS-032, a selective cyclin-dependent kinase inhibitor, is an effective agent for treatment of AML; howe...

BACKGROUND The sentinel node (SN) is defined as the first node in the lymphatic system that drains a tumor site. If the SN is not metastatic, then all other nodes should also be disease-free. We used serial sections and immunohistochemical (IHC) staining to examine both sentinel and non-sentinel nodes (non-SNs). MATERIALS AND METHODS From July 2001 to March 2003, 18 patients (median age, 48 y...

With the popularity of Social Networking Services (SNS), more and more sensitive information are stored online and associated with SNS accounts. The obvious value of SNS accounts motivates the usage stealing problem—unauthorized, stealthy use of SNS accounts on the devices owned/used by account owners without any technology hacks. For example , anxious parents may use their kids' SNS accounts t...