Perhaps no ancient Greek practice is more opaque to us than the Athenian institution of ostracism. Scholars have repeatedly labeled it bizarre, intrin­ sically paradoxical, and exotic. If we follow Darnton’s exhortation (1984: 5), however, our puzzlement is not a cause for dismay, but a signal of fertile territory for the acquisition of a new perspective on the ancient Greek past. In many ways,...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 204 No. 5 683–696 www.jcb.org/cgi/doi/10.1083/jcb.201307158 JCB 683 Correspondence to Tsuyoshi Morita: [email protected] Abbreviations used in this paper: ARP, actin-related protein; BS3, bis(sulfosuccinimidyl) suberate; ChIP, chromatin immunoprecipitation; CHX, cycloheximide; DBD, DNA binding domain; G-actin, globular ac...

Neuropilin-1 (NRP1) has been identified as a VEGF-A receptor. DJM-1, a human skin cancer cell line, expresses endogenous VEGF-A and NRP1. In the present study, the RNA interference of VEGF-A or NRP1 suppressed DJM-1 cell proliferation. Furthermore, the overexpression of the NRP1 wild type restored shNRP1-treated DJM-1 cell proliferation, whereasNRP1 cytoplasmic deletionmutants did not. A co-imm...

Telomeres maintain the integrity of linear chromosomes by preventing the unsolicited recruitment of DNA repair machineries to chromosome ends (de Lange, 2009; Dehé and Cooper, 2010; Jain and Cooper, 2010) and engaging telomerase to solve the end replication problem (Greider and Blackburn, 1985; Artandi and Cooper, 2009). At a distinct site on the chromosome, centromeres mediate the attachment o...

CRYSCOR is a periodic post-Hartree–Fock program based on local functions in direct space, i.e., Wannier functions and projected atomic orbitals. It uses atom centered Gaussians as basis functions. The Hartree–Fock reference, as well as symmetry information, is provided by the CRYSTAL program. CRYSCOR presently features an efficient and parallel implementation of periodic local second order Møll...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 4 595–608 www.jcb.org/cgi/doi/10.1083/jcb.201409142 JCB 595 *L. Luo, H. Wang, and C. Fan contributed equally to this paper. Correspondence to Yu Cai: [email protected] Abbreviations used in this paper: Arm, Armadillo; Bam, bag of marbles; CB, cystoblast; ChIP, chromatin immunoprecipitation; Dally, division abnormally delayed; Dpp...

Correct spindle position is an essential feature of cell division from yeast to man. In animal cells, the cleavage furrow is specified so as to bisect the mitotic spindle. Therefore, correct orientation of the spindle along a given axis, as well as its accurate placement on this axis (hereafter collectively referred to as “spindle positioning” for simplicity), is critical for dictating the rela...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 1 129–142 www.jcb.org/cgi/doi/10.1083/jcb.201411087 JCB 129 *E.C. Roberson and W.E. Dowdle contributed equally to this paper. Correspondence to Jeremy F. Reiter: [email protected] Abbreviations used in this paper: Adcy3, Adenylyl cyclase 3; E, embryonic day; LAP, localization and affinity purification; MEF, mouse embryonic ...