OBJECTIVES Closed minimal extracorporeal circulation (MECC) systems currently do not represent the standard of surgical care for open-heart surgery. Yet, considering the beneficial results reported for coronary artery bypass graft (CABG) surgery, we used an MECC system in aortic valve replacement (AVR) and analysed the effects on intraoperative microvascular perfusion in comparison with convent...

BACKGROUND AND PURPOSE Type 2 FCD is one of the main causes of drug-resistant partial epilepsy. Its detection by MR imaging has greatly improved surgical outcomes, but it often remains overlooked. Our objective was to determine the prevalence of typical MR imaging criteria for type 2 FCD, to provide a precise MR imaging pattern, and to optimize its detection. MATERIALS AND METHODS We retrospe...

Focal cortical dysplasias (FCDs) are increasingly diagnosed as a cause of symptomatic focal epilepsy in paediatric and adult patients. However, little is known about the clinical characteristics of epilepsy in these patients. In order to elucidate the clinical characteristics of their epilepsy, 120 pharmacoresistant patients including children and adults with histologically proven FCD were stud...

Urban rivers flowing through cities are places of recreation and relaxation for citizens. However, these sometimes contaminated by Escherichia coli (E. coli). Therefore, the purpose this study was to develop a simple method investigate E. contamination in river water. From May October 2019, water samples were collected from five locations Toga River Kobe City, Japan, fecal coliform density (FCD...

Focal cortical dysplasias (FCDs) are a range of malformations of cortical development each with specific histopathological features. Conventional radiological assessment of standard structural MRI is useful for the localization of lesions but is unable to accurately predict the histopathological features. Quantitative MRI offers the possibility to probe tissue biophysical properties in vivo and...

Focal malformations of cortical development, including focal cortical dysplasia (FCD), are among the most common causes of intractable epilepsy in children. In this issue of Brain, Jansen and colleagues provide evidence that hemimegalencephaly (HMEG) and FCD type IIa result from mosaic mutations in components of the PI3K/Akt/ mTOR (mammalian target of rapamycin) pathway, i.e. PI3KCA, AKT3, or P...

The use of Floating Car Data (FCD) systems for the generation of traffic information has been discussed in numerous publications, many of which are based on simulated data or on a small number of vehicles collecting data over a limited time span. We present FLEET, a real-world FCD system, which has been continuously operating since 2003, collecting data from thousands of taxis in the Vienna reg...

Objective To characterize the PET-MRI co-registration of hypometabolic patterns in focal cortical dysplasia (FCD) types I and II provide some suggestions presurgical evaluation epilepsy surgery. Methods We retrospectively analyzed imaging data from a cohort 83 patients with histologically confirmed FCD II. Hypometabolic were classified into 4 types: bottom sulcus hypometabolism (BOSH), single i...

In this paper we present a novel randomized block coordinate descent method for the minimization of a convex composite objective function. The method uses (approximate) partial second-order (curvature) information, so that the algorithm performance is more robust when applied to highly nonseparable or ill conditioned problems. We call the method Flexible Coordinate Descent (FCD). At each iterat...

We studied the accuracy of the discrete dipole approximation (DDA) for simulations of absorption and scattering spectra by gold nanoparticles (spheres, cubes, and rods ranging in size from 10 to 100 nm). We varied the dipole resolution and applied two DDA formulations, employing the standard lattice dispersion relation (LDR) and the relatively new filtered coupled dipoles (FCD) approach. The DD...