BACKGROUND Carinal hooks increases difficulty at endotracheal intubation. Amputation of the carinal hook during passage and malpositioning of the tube to the hook are some of the potential problems related with left-sided Carlens double lumen tube (DLT). This article reports an amputation of the hook during a difficult selective intubation and aimed at calling the attention to complications ass...

To the Editor:—We read with great interest the case report on the application of a newly designed right-sided, double-lumen endobronchial tube (R-DLT) in patients with a very short right mainstem bronchus. However, in citing our work on the improvement of the endobronchial positioning of the R-DLT, Hagihira et al. stated that we modified the design of the bronchial cuff and that these changes s...

Escalation with overdose control (EWOC) is a Bayesian adaptive phase I clinical trial design that produces consistent sequences of doses while controlling the probability that patients are overdosed. However, this design does not take explicitly into account the time it takes for a patient to exhibit dose limiting toxicity (DLT) since the occurrence of DLT is ascertained within a predetermined ...

Cumulative exposure to multiple early life stressors is expected affect behavioral development, causing increased susceptibility neuropsychiatric disorders. The present study was designed mimic such conditions in a rat model impairments during adolescence and adulthood. Female Wistar rats (n = 32; 140–150 gm) were switched low protein (LP; 8% protein) or control (20% diet 15 days prior concepti...

There is scientific evidence that an anticipated difficult airway must be managed with the patient being awake. The GlideScope has been proven to be a useful device to intubate the trachea in some instances when difficult airway is present, and particularly in the awake patient. It has also been used for double lumen tube (DLT) in the anaesthetized patient, but its use with DLT in both circumst...

BACKGROUND Video assisted thoracoscopic surgery (VATS) has been successfully used for thymectomy in myasthenia gravis (MG). Thoracoscopic thymectomy (TT) is usually done under general anesthesia with double lumen tubes (DLT). The aim of this study is evaluation of two lung ventilation through single lumen tubes (SLT) during TT. METHODS In this prospective randomized study, TT was done in 30 p...

This study investigated the role of lung vagal afferents in the respiratory-related evoked potential (RREP) response to inspiratory occlusions by using double-lung transplant recipients as a lung denervation model. Evoked potential recordings in response to inspiratory occlusions were obtained from 10 double-lung transplant (DLT) recipients with normal lung function and 12 healthy control (Nor)...

BACKGROUND The tolerability of molecularly targeted agents in older patients has not been specifically examined. Adverse event data from clinical trials in the Princess Margaret Hospital Phase II Consortium database were analyzed to address this question. METHODS The Consortium database collects trial information on all patients treated with either a molecularly targeted agent alone or in com...

In distributed computing systems, a critical concern is to efficiently partition and schedule the tasks among available processors in such a way that the overall processing time of the submitted tasks is at a minimum. On a network of workstations, using parallel virtual machine communication library, we conducted distributed image-processing experiments following two different scheduling and pa...