alpha-Dystroglycan (DG) has been identified as the cellular receptor for lymphocytic choriomeningitis virus (LCMV) and Lassa fever virus (LFV). This subunit of DG is a highly versatile cell surface molecule that provides a molecular link between the extracellular matrix (ECM) and a beta-DG transmembrane component, which interacts with the actin-based cytoskeleton. In addition, DG exhibits a com...

We further investigate the high order positivity-preserving discontinuous Galerkin (DG) methods for linear hyperbolic and radiative transfer equations developed in [14]. The DG methods in [14] can maintain positivity and high order accuracy, but they rely both on the scaling limiter in [15] and a rotational limiter, the latter may alter cell averages of the unmodulated DG scheme, thereby affect...

The dystroglycans (alpha-DG and beta-DG), which play important roles in the formation of basement membranes, have been well studied in skeletal muscle and nerve, but their expression and localization in intestinal epithelial cells has not been previously investigated. Here, we demonstrated that the DG complex, composed of alpha-DG, beta-DG, and utrophin, is specifically expressed in the basolat...

OBJECTIVE 3-Deoxyglucosone (3-DG), a highly reactive intermediate of the glycation reaction, has been suggested to contribute to the development of diabetes complications. To verify this hypothesis, we assessed the relation between serum 3-DG concentrations and the severity of diabetic microangiopathy in diabetic patients. RESEARCH DESIGN AND METHODS We conducted a high-performance liquid chr...

The Danshen-Gegen formula (DG) is a traditional Chinese herbal formula which has long been used to treat cardiovascular disease. DG was found to be a cardiovascular tonic in our recent research. However, a comprehensive investigation of the molecular mechanism of DG in cardiovascular disease has not been performed. The aim of this study was to clarify the transcriptional profiling of genes modu...

Introduction: Cephalometry is an efficient tool for anthropometric studies. This study sought to assess facial dimensions and types of adults residing in Qazvin (Iran) and Dera Ghazi (DG) Khan (Pakistan). Methods: In this cross-sectional study, a total of 300 ethnic populations of Qazvin and 365 ethnic populations of DG Khan aged between 18-55 years were randomly selected and evaluated. Th...

The dentate gyrus (DG) of the hippocampus has a central role in learning and memory in adult rodents. The DG is generated soon after birth, although new neurons continue to be generated in the DG throughout life. The proneural factors Mash1 (Ascl1) and neurogenin 2 (Ngn2) are expressed during formation of the DG but their role in the development of this structure has not yet been addressed. Her...

iii Dedication I would like to dedicate my thesis to my parents, Ken and Marianne Ehresman. iv Abstract Females exhibit superior object location memory (OLM) compared to males, but the reasons for this sex difference remains unknown. This thesis investigates the role of the dentate gyrus (DG) in an OLM task in normal rats (Experiment 1) and after bilateral adrenalectomy (ADX; Experiment 2). ADX...

MCL01 64/F PB 7 IVB Yes NA PR NA MCL02 84/F PB 8 IVB No 94 new Dg none MCL03 66/M PB 6.95 IVB No NA new Dg del11q MCL04 60/M PB 7.64 IVB No NA new Dg del17p MCL05 57/M PB 5.54 IVA No 47 new Dg none MCL06 57/M PB 5.65 IVA No NA new Dg none MCL07 76/M PB 8.5 IVB No 37 new Dg NA MCL08 68/M PB 8.5 IVB No 70 new Dg del17p, del11q MCL09 41/M PB 5.38 IVA No 17 new Dg none MCL10a 71/M PB 10 IVA Yes 50 ...