INTRODUCTION Myasthenia gravis (MG) is an autoimmune disease characterized by weakness and fluctuating pathological tiredness of cross-striped muscle with improvement after rest. GOAL To compare the outcomes of treatment in myasthenic crisis therapy and conventional therapy with high doses of human immunoglobulin. Epidemiological research, mainly retrospective, partly prospective, descriptive...

when stretcher came to unit and i was put in my bed, nursing personnel of surgical ward said to me hello. i had seen their face from yesterday night when they were transferring patients from emergency ward to this unit.  in that time, i had the role of emergency ward assistant manager. today, i am a weak patient that even is unable for smallest movement. cause of my admission to hospital is mus...

background: several concomitant disorders especially thyroid abnormalities have been reported in patients with myasthenia gravis (mg). we aimed to estimate the frequency and pattern of thyroid disorders in iranian patients with mg.all consecutive patients with mg referred to neurology clinic of rasool-e-akram hospital during 2006-2007 were enrolled. methods: all patients underwent clinical asse...

background and aims:  myasthenia gravis (mg) is a chronic autoimmune disorder of neuromuscular transmission resulting in muscle weakness. while mg reportedly occurs in all ethnic groups, relative differences in disease prevalence are yet to be determined. the aim of this study was evaluation  of incidance and other disorders with it in kerman province of iran. methods: all patients with mg that...

Patients with myasthenia gravis show sensitivity to non-depolarizing neuromuscular blocking drugs, but little is known about differences in this sensitivity between types of myasthenia. In 10 patients with ocular myasthenia gravis and 10 with generalized myasthenia gravis, twitch tension was monitored in the adductor pollicis muscle by supramaximal train-of-four stimulation of the ulnar nerve d...

A 79-year-old man with previous bulbar poliomyelitis developed dysphagia and was diagnosed as having post-polio syndrome. Over 2 years, his swallowing deteriorated and he suffered an aspiration pneumonia. Only after the subsequent development of fatigue and facial weakness was myasthenia gravis diagnosed. Diagnostic criteria for post-polio syndrome include the exclusion of all other neurologica...

Myasthenia gravis in one member each of two sets of twins is described. A 17 year old girl developed generalized myasthenia gravis at the age of 14 years, while her monozygotic twin sister has remained in good health during a three year period of observation. Another patient was a 19 year old woman with the onset of generalized myasthenia gravis at the age of 11 years, and her dizygotic twin si...

BACKGROUND Celiac disease is described in association with several autoimmune diseases, but rarely with myasthenia gravis. CASE REPORT We describe the case of a 31-year-old white woman with celiac disease who presented manifestations related to a hyperactive immune system, including macroamylasemia, false-positive anti-HCV, positive antinuclear antibody, and Raynaud's phenomenon. The introduc...

Rearrangement of T cell receptor (TCR) V8-J8 genes has been analyzed in 20 myasthenia gravis (MG) cases and 17 controls (blood donors) using the seminested polymerase chain reaction (PCR). Unlike the healthy subjects the majority of patients demonstrated a monoor oligoclonal type of rearrangement of TCR V51-6-J51 genes. It is suggested that T lymphocytes may undergo clonal expansion in myasthen...