Introduction Generalized atrophic benign epidermolysis bullosa (GABEB) is a form of nonlethal junctional epidermolysis bullosa characterized by universal alopecia and atrophy of the skin. We report a deficiency of the 180-kD bullous pemphigoid antigen in three patients with GABEB from unrelated families. We screened specimens of clinically normal skin from nine junctional epidermolysis bullosa ...

The effects of the composition and rheology of the fermentation medium on the antibiotic production by Streptomyces hygroscopicus CH-7 were studied. To increase the yields of hexaene H-85 and elaiophylin, the basic fermentation medium was reformulated using different carbon (glucose, lactose, ribose, fructose and trehalose) and nitrogen (isatin-Schiff bases) sources. The maximum yields of hexae...