Biologically formed calcite crystals have unique, sculptured shapes that are believed to be regulated locally by speci"c macromolecules and by directional #ux of ions into the microenvironment of crystal growth. This paper describes a biologically inspired synthesis of patterned calcitic "lms using micropatterned self-assembled monolayers (SAMs) which served as spatially constrained microenviro...

In the past decade, self-assembled monolayers (SAMs) have received a great deal of attention for their fundamental importance in understanding interfacial properties as well as for their potential applications in molecular technologies. SAMs have been used in the design of various interfaces for chemical sensors, nonlinear optical materials, optical switches, and high density memory devices. Th...

Self-assembled monolayers (SAMs) containing azobenzene moieties are very attractive for a wide range of applications, including molecular electronics and photonics, bio-interface engineering and sensoring. However, very little is known about the aggregation and photoswitching behavior that azobenzene units undergo during the SAM formation process. Here, we demonstrate that the formation of thio...

The structure and conformation of self-assembled monolayers (SAMs) derived from the adsorption of a specifically designed double-chained partially fluorinated thiol having the formula 12,12,13,13,14,14,15,15,16,16,17,17,18,18,19,19,19-heptadecafluoro-2-tetradecylnona-decane-1-thiol (2) onto the surface of evaporated gold were examined by ellipsometry, contact angle goniometry, polarization modu...

In spite of the unequivocal efficacy of statins in reducing primary and secondary cardiovascular events, the use of these drugs in a considerable number of patients is limited because of statin intolerance, mainly statin-associated muscle symptoms (SAMS). SAMS encompass a broad spectrum of clinical presentations, including mild muscular aching and other types of myalgias, myopathy with the sign...

Alkanethiols carrying ethylene glycol units (EGn, n = 3 or 6) with amine termini (EG3NH2 or EG6NH2) were coadsorbed with a “diluent”, hydroxylterminated alkanethiol (EG3OH), to form mixed self-assembled monolayers (SAMs). The mixed SAMs were characterized, and hexameric peptide ligand His-Trp-Arg-GlyTrp-Val (HWRGWV), which shows affinity binding toward the Fc (constant fragment) of human immuno...

Due to the ease of their preparation and their relatively high stability, self-assembled monolayers (SAMs) are promising candidates to be used in the development of microand nanostructured materials with various functionalities. The formation of SAMs is mainly driven by a combination of molecule– substrate and intermolecular interactions. So far, most of the fundamental studies of SAMs structur...

Aerobic capacity decreases with age, in part because of an age-dependent decline in maximum heart rate (mHR) and a reduction in the intrinsic pacemaker activity of the sinoatrial node of the heart. Isolated sinoatrial node myocytes (SAMs) from aged mice have slower spontaneous action potential (AP) firing rates and a hyperpolarizing shift in the voltage dependence of activation of the "funny cu...

Non-specific adsorption (NSA) of biomolecules is a persistent challenge in microfluidic biosensors. Microfluidic biosensors often have immobilized bioreceptors such as antibodies, enzymes, DNAs, etc, via linker molecules such as SAMs (self-assembled monolayers) to enhance immobilization. However, the linker molecules are very susceptible to NSA, causing false responses and decreasing sensitivit...

Student and Administrative Management Systems (SAMS) have been widely implemented in educational institutions and universities worldwide. SAMS is designed to assist and improve performed by administrators, academics, and students. However, with widespread usage of these systems in universities throughout the world, the evaluation of the task-enhancing features of such systems to users becomes c...