☆ Funding was provided by NIH/NIA (R01AG024119 a ⁎ Corresponding author. E-mail address: [email protected] (M. Gurven). 1090-5138/$ – see front matter © 2014 Elsevier Inc. Al http://dx.doi.org/10.1016/j.evolhumbehav.2013.09.002 Article history: Initial receipt 31 May 2013 Final revision received 7 September 2013

El Contador Público es un profesionista que se encarga entre otras actividades de la preparación y análisis los estados financieros; determinación liquidación las contribuciones federales; costos; asesor financiero; auditoría apoyo a alta dirección. Una parte importante del trabajo puede desempeñar lo constituye auditoria consiste básicamente en revisión información financiera una entidad econó...

News impact analysis has become a common task conducted by finance researchers, which involves reading and selecting news articles based on themes sentiments, pairing events relevant stocks, measuring the of selected stock prices. To facilitate more efficient selection, topic modeling can be applied to generate topics out large number documents. However, there is very limited existing literatur...

Introduction: Solanezumab is an anti-amyloid monoclonal antibody in clinical testing for treatment H.L.-S., E.S., K.C ployees and minor sha the Alzheimer’s Assoc for the Alzheimer’s A Lilly and Company an full-time employee of Therapies, Biogen, Bi Hoffman LaRoche, M ences, Suven, Transiti imental agents and rec CME program; she has entech, Lilly/NIA, Me http://dx.doi.org/10.1

We herein provide a thorough description of new transgenic mouse models for dentatorubral-pallidoluysian atrophy (DRPLA) harboring a single copy of the full-length human mutant DRPLA gene with 76 and 129 CAG repeats. The Q129 mouse line was unexpectedly obtained by en masse expansion based on the somatic instability of 76 CAG repeats in vivo. The mRNA expression levels of both Q76 and Q129 tran...

The specific intracellular inhibition of protein activity at the protein level is a highly valuable tool for the validation or modulation of cellular processes. We demonstrate here the use of designed ankyrin repeat proteins (DARPins) as tailor-made intracellular proteinase inhibitors. Site-specific proteolytic processing plays a critical role in the regulation of many biological processes, ran...

We thank Hewitt Associates for providing the data analyzed in this paper. We are particularly grateful to Consortium). The opinions and conclusions expressed are solely those of the authors and do not represent the opinions or policy of NIA, SSA, any other agency of the U.S. Federal Government, or the NBER.