Among all microRNAs (miRNAs) in 12 plant species investigated in this study, only miR398 targeted the copper chaperone for superoxide dismutase (CCS). The nucleotide sequences of miRNA binding sites were located in the mRNA protein-coding sequence (CDS) and were highly homologous. These binding sites in CCS mRNA encoded a conservative GDLGTL hexapeptide. The binding sites for miR398 in the CDS ...

Recent studies have shown that homozygous Mn superoxide dismutase (Sod2) gene-knockout mice (Sod2(-/-)) die shortly after birth with extensive myocardial injury, whereas heterozygous mutants (Sod2(+/-)) are phenotypically normal in room air. In the current study, we showed that Sod2(+/-) mice with approximately 50% of normal pulmonary MnSOD activity and normal levels of lung CuZnSOD, catalase, ...

Preparation and characterization of two new site-directed mutant copper-zinc superoxide dismutase proteins from Saccharomyces cerevisiae, i.e., His46Cys (H46C) and His120Cys (H120C), in which individual histidyl ligands in the copper-binding site were replaced by cysteine, are reported here. These two mutant CuZnSOD proteins may be described as type 2 (or normal) rather than type 1 (or blue) co...

We have suggested that intestinal microflora reduces the activity of the antioxidant enzyme superoxide dismutase (SOD) in the mouse cecal mucosa. In this study, gnotobiotic mice were used to examine the species of intestinal microflora influencing SOD activity in the cecal mucosa. The total SOD activity in the cecal mucosa of each germ-free (GF), gnotobiotic mouse with Escherichia coli, Lactoba...

Superoxide dismutase (SOD) is the first line of defense against oxidative damage. Malathion an organophosphate insecticide and can induce production reactive oxygen species (ROS) cause intracellular stress. The present study was undertaken to examine effects malathion on SODs activity their transcriptional levels in Oxya chinensis (Thunberg) (Orthoptera: Acrididae). results showed that total SO...

Salinity is affecting plant growth and development. Low concentration of hydrogen peroxide (H2O2) has shown to be effective against various stress factors. In this study, effect different H2O2 priming methods on growth, physiological biochemical parameters in three wheat varieties (NKÜ Lider, Sultan-95, Tosunbey) under salt were investigated. Salt (0 160 mM NaCl) was applied gradually 100 µM (-...

In the study, effects of selenium on intestinal tissue morphology, antioxidant-related genes, and flora grass carp (Ctenopharyngodon idella) were studied. For this purpose, 180 healthy carps (20.0±2.0 g) randomly divided into three groups with replicates each: corresponding amount anhydrous sodium selenite was added to make experimental water solutions different concentrations, including 0 μg/L...

The aim of the present study was assessment sub-chronic effects silver (AgNPs) and gold nanoparticles (AuNPs) 40 nm primary size either stabilised with citrate (CIT) or coated polyethylene glycol (PEG) on freshwater invertebrate Gammarus fossarum. Silver nitrate (AgNO3) used as a positive control in order to contribution ions potentially released from AgNPs observed effects. A multibiomarker ap...