The placement of dental implants in the anterior maxilla is a challenge for clinicians because of patients’ exacting esthetic demands and difficult pre-existing anatomy. This article presents anatomic and surgical considerations for these demanding indications for implant therapy. First, potential causes of esthetic implant failures are reviewed, discussing anatomic factors such as horizontal o...

This longitudinal study identified factors of couples' marital friendship in the beginning months of marriage that predicted stability versus decline in marital satisfaction over the transition to parenthood. Newlywed couples (N = 130) were followed longitudinally for 6 years. Forty-three couples because parents, and 39 childless couples served as a control group. Couples were interviewed about...

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introduction: recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (ms). molecular target therapy studies in ms have revealed that connexin-43 (cx43) and aquaporin-4 (aqp4) contents of astrocytes undergo expression alteration. fluoxetine had some effects in ms patients unrelated to its known antidep...

Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidep...

The confluence of factors driving urban growth is highly complex, resulting from a combination of ecological and social determinants that co-evolve over time and space. Identifying these factors and quantifying their impact necessitates models that capture both why urbanization happens as well as where and when it happens. Using a database that links five satellite images spanning 1976–2001 to ...

evaporation. Taking the mean density and Bond albedo of a typical Vulcanoid to be the same as that of Mercury, we ®nd that objects with radii z satisfying 0:1 ( z ( 50 km can evade both drag and evaporation in the Vulcanoid belt. This is one of the most dynamically stable regimes in the entire Solar System. If further searches do not detect any intra-mercurial objects, this is a strong indicato...

This study aimed to investigate the effects of polymorphisms of the flavin-containing mono-oxygenase 3 (FMO3) and flavin-containing mono-oxygenase 6 (FMO6) genes on the pharmacokinetics of sulindac sulfide, the active metabolite of sulindac, in patients with preterm labor. Ten single-nucleotide polymorphisms (SNPs) were genotyped, and plasma sulindac sulfide concentrations were measured at 0, 1...