We have previously reported lack of expression of a polypeptide designated L3 in infant acute lymphoblastic leukemia (ALL). Expression of L3 occurred predominantly in older children with pre-B ALL. We have recently reported the expression during B cell ontogeny of two other polypeptides, designated L2 and L4 with a similar Mr as L3, which were identified as phosphorylated and non-phosphorylated...

Henöch-Schonlein Purpura (HSP) merupakan kondisi vaskulitis pembuluh darah kecil yang paling sering terjadi pada anak, dengan insidensi 10-20 kasus per 100.000 anak setiap tahunnya. Lebih dari 90% pasien berusia dibawah 10 tahun usia rata-rata 6 tahun. Penyakit ini ditandai lesi kulit spesifik berupa purpura nontrombositopenik, artritis, nyeri abdomen dan perdarahan saluran cerna, serta dapat p...

Mammalian cells constitutively express a cytosolic and nuclear form of heat shock protein (hsp) 70, referred to here as hsp 73. In response to heat shock or other metabolic insults, increased expression of another cytosolic and nuclear form of hsp 70, hsp 72, is observed. The constitutively expressed hsp 73, and stress-inducible hsp 72, are highly related proteins. Still unclear, however, is ex...

This review will focus on recent knowledge related to circulating autoantibodies (AAbs) to tumor-associated antigens (TAAs) in epithelial ovarian carcinoma. So far, the following TAAs have been identified to elicit circulating AAbs in epithelial ovarian carcinoma: p53, homeobox proteins (HOXA7, HOXB7), heat shock proteins (HSP-27, HSP-90), cathepsin D, cancer-testis antigens (NY-ESO-1/LAGE-1), ...