In the title compound, C(13)H(11)BBrFO(3), the dioxy-boron fragment is close to co-planar with the benzene ring to which the B atom is connected [dihedral angle = 8.96 (4)°]. The dihedral angle between the two benzene rings is 14.8 (2)°. One of the OH groups is engaged in an intra-molecular O-H⋯O hydrogen-bonding inter-action. The second OH group is involved in inter-molecular hydrogen bonding,...

Fluorine-18 fluorodeoxyglu-cose positron emission tomography in mature T-cell and natural killer cell ma-lignancies. Recently in Blood, Schonthal and colleagues reported in an elegant study that green tea polyphenols interact directly with bortezomib and other boronic acid–based proteasome inhibitors and block their anticancer effects. 1 This subject has significant practice implications. By re...

The title compound, 2-(CH(3)CH(2)CH(2)CH(2)O)C(6)H(4)B(OH)(2), exists as a centrosymmetric hydrogen-bonded dimer. Dimers are linked via C-H⋯π and π-π [with closest C⋯C contact of 3.540 (3) Å] inter-actions to produce a two-dimensional array.

The inhibitory effect of arylboronic acids which act as a transition state analogue for certain peptidases is efficiently intensified by added saccharides: this finding enables us to control the enzyme activity by a combination of arylboronic acids and polyols including sugars. In particular, the combined system of 3-biphenylboronic acid and D-glucose strongly inhibited the hydrolysis reaction ...

Two classes of addition/cycloaddition cascade reactions of hydrazinecarbodithioate (1) have been developed under mild reaction conditions. Reaction of hydrazinecarbodithioate (1) with formaldehyde solution (2) and propiolic acid (3) gives 3-propargyl-5-thiol-2,3-dihydro-1,3,4-thiadiazoles (5) via a decarboxylative coupling/cycloaddition domino sequence. When propiolic acid (3) is switched to ph...

Control of boronic acid solution speciation is presented as a new strategy for the chemoselective synthesis of boronic esters. Manipulation of the solution equilibria within a cross-coupling milieu enables the formal homologation of aryl and alkenyl boronic acid pinacol esters. The generation of a new, reactive boronic ester in the presence of an active palladium catalyst also facilitates strea...

Boronic-acid-based dyes have been widely studied in the past decade as potential sensors for sugars and carbohydrates, owing to the strong interaction of boronic acid and diols. In this work, two boronic-acid-appended metalloporphyrins were synthesized by new routes and tested as potential sugar and carbohydrate sensors. Boronic acid substituents were attached either to a βpyrrolic position ((2...

Abstract (4+3)-Annulations are incredibly versatile reactions which combine a 4-atom synthon and 3-atom to form both 7-membered carbocycles as well heterocycles. We have previously reviewed transition-metal-catalyzed (4+3)-annulations. In this review, we will cover examples involving bases, NHCs, phosphines, Lewis Brønsted acids some rare of boronic acid catalysis photocatalysis. analogy our pr...