Mahmoud Yousefifard

Physiology Research Center and Department of Physiology, Faculty of Medicine, Iran University of Medical Sciences; Tehran, Iran.

[ 1 ] - Effect of Active and Passive Exposure to Cigarette Smoke on Lipid Profile of Children and Adolescents; A Systematic Review and Meta-Analysis

Background: The present systematic review and meta-analysis is designed in order to assess the association between passive and active smoking and lipid profile of children and adolescents. Materials and Methods:  An extensive search was done in databases of Medline, EMBASE, Web of Science, Scopus and CINAHL until October 2017. Two independent researchers screened articles and in the next step, ...

[ 2 ] - Seroprevalence of Hepatitis B and C Virus Infection in Children with Chronic Kidney Diseases; A Historical Cohort Study

Background: The prevalence of hepatitis B and C in Iranian children with chronic kidney disease is limited. Therefore, the present study intends to assess the prevalence of hepatitis B and C in children with chronic kidney disease (CKD).Method: The present study is a historical cohort study which was conducted in a window period of 25 years in Children’s Medical Center in Tehran, 1991-2016. Dat...

[ 3 ] - Accuracy of Pediatric Emergency Care Applied Research Network Rules in Prediction of Clinically Important Head Injuries; A Systematic Review and Meta-Analysis

Objective: the present meta-analysis was designed to determine the value of Pediatric Emergency Care Applied Research Network (PECARN) rule in prediction of clinically important traumatic brain injury (ciTBI).Methods: Extensive search was conducted in the databases of Medline, Embase, Scopus, Web of Sciences, Cinahl up to the end of August 2017. The search records were screened and summarized b...

[ 4 ] - Efficacy of Neuromodulation in Fecal Incontinence in Children; A Systematic Review and Meta-Analysis

Background: The results of existing studies regarding the use of neuromodulation in fecal incontinence (FI) are contradictory and therefore, a definitive conclusion cannot be made in this regard. Therefore, the aim of the present study is to evaluate the effectiveness of neuromodulation in controlling FI in children through a systematic review.Methods: A decision was made to perform the search ...

[ 5 ] - Human Adipose-Derived Stem/Stromal Cells from Children or Adults?

Discovering a cell type with the highest efficiency and the least side-effects is one of the priorities of scientists active in this field. Of all the cells, mesenchymal stem cells have been and still are of interest to the researchers for use in pre-clinical and clinical studies due to being easily accessible, pluripotency, secretion of numerous growth factors, low risk of immunological reject...

[ 6 ] - Diagnostic Value of Technetium-99m-Dimercaptosuccinic Acid Scintigraphy in Prediction of Vesicoureteral Reflux in Children with First-time Febrile Urinary Tract Infection

Background: Imaging modalities such as voiding cystourethrography (VCUG), direct radionuclide cystography (DRNC), and renal cortical scintigraphy (RCS) with technetium-99m dimercaptosuccinic acid (Tc-99mDMSA), are helpful in detecting possible abnormalities of urinary tract such as vesicoureteral reflux (VUR). However, there are confounding data regarding the preference of these modalities. In ...

[ 7 ] - Prediction of Clinically Important Traumatic Brain Injury in Pediatric Minor Head Trauma; proposing Pediatric Traumatic Brain Injury (PTBI) Prognostic Rule

Background: The present study assesses independent predictors of clinically important traumatic brain injury (ciTBI) in order to design a prognostic rule for identification of high risk children with mild head injury. Materials and Methods: In a retrospective cross-sectional study, 3,199 children with mild traumatic brain injury (TBI) brought to emergency ward of three hospitals in Tehran, Iran...

[ 8 ] - Value of Plasma/Serum Neutrophil Gelatinase-Associated Lipocalin in Detection of Pediatric Acute Kidney Injury; a Systematic Review and Meta-Analysis

Background: Major attention has been drawn to the prognostic value of plasma/serum neutrophil gelatinase-associated lipocalin (NGAL) in detection of acute kidney injury (AKI) in children, but still no consensus has been reached. Accordingly, the present study aimed to assess the diagnostic value of this biomarker in detection of acute kidney injury in children through a systematic review and me...

[ 9 ] - Diagnostic Value of Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Detection of Pediatric Acute Kidney Injury; a Systematic Review and Meta-Analysis

Background: Two questions about diagnostic value of urinary neutrophil gelatin associated lipocalin (uNGAL) in detection of acute kidney injury (AKI) in children have remained unanswered; first, which cut-off point of uNGAL has the highest value in detection of AKI; and second when is the best time for measuring this biomarker in a patient? Accordingly, the present study aimed to conduct a syst...

[ 10 ] - The Value of Serum Β-Subunit of Human Chorionic Gonadotropin Level in Prediction of Treatment Response to Methotrexate in Management of Ectopic Pregnancy; a Systematic Review and Meta-Analysis

Background: No consensus has been reached on prognostic value of serum concentration of β (beta) subunit of human chorionic gonadotropin (β-hCG) in treatment response to methotrexate in management of ectopic pregnancy. Therefore, the present study aimed to evaluate this subject through a systematic review and meta-analysis. Materials and Methods: An extensive literature search on online databas...

[ 11 ] - Etiology and Outcome of Chronic Kidney Disease in Iranian Children

Background Considering the significant geographical and ethnical differences in pattern of incidence, etiology and outcome of chronic kidney disease (CKD), the present study aimed to assess the etiology and outcome of CKD in Iranian children. Materials and Methods In a cross-sectional study etiology and outcome of 372 children aged 3 months to 18 years with CKD was studied during the period 199...

[ 12 ] - Blood Pressure Nomograms by Age and Weight for Iranian Children and Adolescents

Background: Normal standard references of blood pressure (BP) for children and adolescents have been suggested to be constructed based on anthropometric indices. Accordingly, we aimed to develop first BP reference percentiles by weight and age for Iranian children aged 3-18 years old. Materials and Methods: A total of 16,246 children and adolescents aged 3-18 years were included from 3 cross-se...

[ 13 ] - Body Mass Index Percentile Curves for 7 To 18 Year Old Children and Adolescents; are the Sample Populations from Tehran Nationally Representative?

Background: The children’s body composition status is an important indicator of health condition evaluated through their body mass index (BMI). We aimed to provide standardized percentile curves of BMI in a population of Iranian children and adolescents. We assessed the nationally representative of sample populations from Tehran. Materials and Methods: A total sample of 14,865 children aged 7-1...

[ 14 ] - Long-Term Survival of Peritoneal Dialysis in Children: A Cohort Study

Background: There is little information about the survival rate of pediatric peritoneal dialysis (PD) patients and its risk factors. Therefore, the aim of the present study was to assess survival rate and its risk factors in Iranian children undergoing PD. ...

[ 15 ] - Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and ‎Meta-analysis

Purpose: The present systematic review and meta-analysis aims to investigate the role of posterior tibial nerve stimulation (PTNS) in the control of fecal incontinence (FI). Methods: Two independent reviewers extensively searched in the electronic databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, CINAHL, and Scopus for the studies published...