Vahid Naseh

Dept. of Biology, Faculty of Biological Sciences, Parand Branch, Islamic Azad University, Parand, Iran

[ 1 ] - The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice

Background & objective: The HER-2 gene is an important on co protein overexpressed in many types of cancers. The current study hypothesized that curcumin downregulates HER-2 and inhibits the signal transduction pathway of PI3K/Akt, MAPK, and activation of NFκB, which could be useful to treat overexpressed-HER-2 hepatocellular carcinom...

[ 2 ] - تاثیر تزریق داخل بطن مغزی CNQX بر اخذ عذا و آب تجمعی در جوجه

 سابقه و هدف: مطالعات انجام شده پیرامون مکانیسم های فیزیولوژیک تنظیم اشتها در پستانداران و پرندگان نشان دهنده دخالت دو دسته از عوامل محیطی و مرکزی است .گلوتامات به عنوان مهم ترین میانجی عصبی تحریکی، در کنترل مرکزی و محیطی اخذ غذا در پستانداران و پرندگان نقش دارد. تزریق داخل بطن مغزی گلوتامات و آگونیست های آن منجر به کاهش شدید اخذ غذا شده است. گیرنده های یونوتروپیک گلوتامات شامل گیرنده های NMDA ...

[ 3 ] - The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats

Background: Cadmium is a potent toxicant and carcinogenic in human and experimental animals. The evidence indicates that cadmium induces aberrant gene expression, inhibition of DNA damage repair, and apoptosis. In this study, we investigated the effects of IP (intraperitoneal) injection of cadmium on mRNA levels expression of Bcl-2 and Bax genes in rat small intestine. <s...

[ 4 ] - Synergistic Effect Of Treadmill Exercise And Green Tea Extract On Cutaneous wound Healing In Diabetic Mice

Aim and Background: In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.   Material and methods: The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic...

[ 5 ] - Effect of Artemisia ciniformis Extract on Expression of NorA Efflux Pump Gene in Ciprofloxacin Resistant Staphylococcus aureus by Real Time PCR

Background: Activity of norA efflux pump is one of the antibiotic resistance mechanisms in ciprofloxacin resistant Staphylococcus aureus. In this study, the effect of Artemisia ciniformis extract on reducing the expression of norA efflux pumps gene in ciprofloxacin-resistant Staphylococcus aureus isolates was studied. Materials and Methods: Ciprofloxacin resistant S. aureus isolates, were trea...