Mohammad Masjedi

[ 1 ] - Different Gene Expressions of Alpha and Beta Glucocorticoid Receptors in Asthmatics

The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...

[ 2 ] - A Pilot Study of Polymorphism of Adrenergic Beta-2 Receptor and Mild Asthma: A Clinical and Pharmacogenetic Study

Glycine allele at codon 16 has previously been associated with the increase in asthma severity, bronchial hyperresponsiveness and also the increase in inhaled corticosteroid dependence. This study was designed to evaluate the genetic alleles in mild asthma.Thirty-four patients with diagnosis of mild asthma (FEV1 ≥ 80%, positive methacholine test) and body mass index (BMI ≤ 30 Kg/m2) were includ...

[ 3 ] - Different Gene Expressions of Alpha and Beta Glucocorticoid Receptors in Asthmatics

The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...

[ 4 ] - A Pilot Study of Polymorphism of Adrenergic Beta-2 Receptor and Mild Asthma: A Clinical and Pharmacogenetic Study

Glycine allele at codon 16 has previously been associated with the increase in asthma severity, bronchial hyperresponsiveness and also the increase in inhaled corticosteroid dependence. This study was designed to evaluate the genetic alleles in mild asthma.Thirty-four patients with diagnosis of mild asthma (FEV1 ≥ 80%, positive methacholine test) and body mass index (BMI ≤ 30 Kg/m2) were includ...

[ 5 ] - Asthma and body mass index in occupational setting

Background :Asthma is the most common respiratory disease with an increasing prevalence. On the other hand, obesity is also a challenging disease compromising health in human communities. This study sought to assess the correlation of asthma and body mass index (BMI) in occupational setting. Methods : This study was conducted in a cable manufacturing company in 2012. A total of 551 workers ...

[ 6 ] - Frequency of tobacco use among students in Varamin city: Results of the first phase of the PAD project study (Tobacco Use Prevention in Schools)

Introduction: Smoking among adolescents is a matter of concern that has attracted the attention of many officials and experts in various fields such as health-care, psychology, and sociology. This study was conducted in 2019 to evaluate the status of smoking in students at the individual and familial levels. Materials and Methods: This study was performed based on the analysis of the results of...