Farzaneh Dehghani

Histomorphometry and Stereology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

[ 1 ] - Anti-Diabetic Effects of Amygdalus Lycioides Spach in Streptozocin-Induced Diabetic Rats

Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugarand abnormalities in insulin secretion and action. There are many anti-diabetic plants, whichmight supply useful sources for developing new medicines that can be used in treatment ofdiabetes mellitus. The primary objective of the present investigation is to evaluate the antidiabeticproperties of the aerial ...

[ 2 ] - Effect of hydroalcoholic extract of caraway on thyroid gland structure and hormones in female rat

Caraway is one of the medicinal plants used for digestion problems, however, it has been reported that the long term use of this plant in large doses might cause hyperthyroidism symptoms such as leanness, hair loss, severe sweating and tremulousness. Therefore, the aim of this study was to evaluate the effect of hydroalcoholic extract of caraway on the level of thyroid hormones and morphologic ...

[ 3 ] - Toxic effects of hydroalcoholic extract of Citrullus colocynthis on pregnant mice

Citrullus colocynthis (CCT) is used in traditional medicine to inhibit the implantation of embryos. The objective of this study was to determine the number of embryos per pregnancy and the mortality rate in pregnant mice. 115 vaginal plug-positive mice were divided into 4 groups. The animals were given 30, 60 and 120 mg/kg hydroalcoholic extract of CCT until 17th day of gestation. Control group...

[ 4 ] - Anti-Diabetic Effects of Amygdalus Lycioides Spach in Streptozocin-Induced Diabetic Rats

[ 5 ] - اثر آلودگی صوتی بر روی کلیه جنین موش سوری (یک بررسی استریولوژیکی)

زمینه: آلودگی صوتی در افراد بالغ سبب آسیب به کلیه‌ها می‌شود اما تأثیر آلودگی‌های صوتی بر روی جنین هنوز ناشناخته باقی مانده است. بنابراین هدف از این مطالعه تأثیر اصوات با شدت زیاد بر روی حجم و ساختمان کلیه‌های در حال تکامل در جنین بوده است. مواد و روش‌ها: 32 موش حامله به 4 گروه 8 تایی تقسیم شدند. مادران باردار در گروه‌های آزمایش از روز 6 بارداری تا یک هفته پس از تولد به میزان 5/2 ساعت در معرض صد...

[ 6 ] - بررسی استریولوژیک اثر غلظت‌های مختلف عصاره آبی قهوه بر روی حجم کلیه

زمینه: قهوه یک نوشیدنی سنتی است که مورد استفاده اغلب مردم دنیا قرار دارد. زیاده‌روی در مصرف این نوشیدنی، سبب بروز عوارض متعددی بر روی بدن می‌شود. در این مطالعه تأثیر غلظت‌های مختلف عصاره آبی دانه قهوه بر روی حجم کلیه توسط روش‎های استریولوژی مورد بررسی قرار گرفت. مواد و روش‌ها: به این منظور 60 موش صحرایی نر از نژاد اسپراگو- داولی با وزن 250-230 گرم به 6 گروه تقسیم شدند. به گروه کنترل آب ( 5/0 می...

[ 7 ] - بررسی استریولوژیکی تعداد گلومرول ها در نارسائی حاد کلیه ناشی از تجویز گلیسرول در موش صحرائی نر

شمارش تعداد گلومرول ها معیار مناسبی برای تشخیص و درمان بیماری های کلیه به حساب می آید. به منظور بررسی این تغییرات در نارسایی حاد کلیه القاء شده توسط گلیسرول در موش صحرایی, از روش های استریولوژی به عنوان شاخص اندازه گیری استفاده شد. در این تحقیق تعداد 24 قطعه موش صحرایی از نژاد اسپراگو-داولی به صورت تصادفی انتخاب و به دو گروه کنترل و آزمایش تقسیم گردیدند. به گروه آزمایش به میزان ده سی سی در ک...

[ 8 ] - Modulatory Effect of Gonadotropins on Rats’ Ovaries after Nandrolone Decanoate Administration: A Stereological Study

Background: Nandrolone decanoate (ND) is an anabolic androgenic steroid (AAS) which influences the ovarian structure and function. We assessed the effects of ND on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of ND. Methods: Six groups of Sprague...

[ 9 ] - Effects of Hydroalcoholic Extract of Matricaria chamomilla on Serum Testosterone and Estradiol Levels, Spermatozoon Quality, and Tail Length in Rat

Background: Matricaria chamomilla (chamomile) is a herb used to treat various human illnesses. The present study was conducted to investigate the effects of chamomile extract on spermatozoon quality, serum levels of estradiol and testosterone, and sperm tail length in male adult rat. Methods: Male Sprague-Dawley rats received extract of chamomile (400 mg/kg once daily, orally) during an 8-week...

[ 10 ] - Effects of the Hydroalcoholic Extract of the Psidium guajava Fruit on Osteoporosis Prevention in Ovariectomized Rats

Background: Several plants have been shown to possess antioxidant and estrogenic properties that can be useful in postmenopausal bone-loss prevention. The present study aimed to investigate the anti-osteoporotic effects of the hydroalcoholic extract of the Psidium guajava (PG) fruit in ovariectomized (OVX) rats.Methods: Sixty female Sprague–Dawley rats were randomly divided into 6 groups: a con...

[ 11 ] - The effect of pentoxifylline on the stereological changes of the vitrified mouse ovarian tissue

Background and Aim: Ovarian vitrification is a technique for assisted reproductive technologies, while ovaries are vulnerable to the damage caused by the freezing procedure. Pentoxifylline has a protective effect as an antioxidant in reducing the free radicals in the culture medium. This study aimed to determine the antioxidant effects of pentoxifylline on the changes stereological vitrified ov...

[ 12 ] - Osteogenesis effect of ginger (Zingiber officinale) hydroalcoholic extract in mouse embryos

Introduction: Ginger in Iranian traditional medicine is known as an effective plant in reducing menopausal symptoms and treating osteoporosis. Therefore, in this study, the effects of ginger on the skeletal system in the fetus and the level of bone formation factors in the mice were investigated. Materials and Methods: In this study, 40 pregnant Balb/c mice were equally divided into four groups...

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