Hoda Abolhasani

Tabriz University of Medical Sciences, Tabriz, Iran

[ 1 ] - In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies

Interference with microtubule polymerization results in cell cycle arrest leading to cell death. Colchicine is a well-known microtubule polymerization inhibitor which does so by binding to a specific site on tubulin. A set of 3',4'-bis (substituted phenyl)-4'H-spiro[indene-2,5'-isoxazol]-1(3H)-one derivatives with known antiproliferative activities were evaluated for their tubulin binding modes...

[ 2 ] - In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies

Interference with microtubule polymerization results in cell cycle arrest leading to cell death. Colchicine is a well-known microtubule polymerization inhibitor which does so by binding to a specific site on tubulin. A set of 3',4'-bis (substituted phenyl)-4'H-spiro[indene-2,5'-isoxazol]-1(3H)-one derivatives with known antiproliferative activities were evaluated for their tubulin binding modes...

[ 3 ] - Relationship between Spiritual Health and Job Performance among Operating Room Personnel Working in Academic Hospitals, Qom, Iran

Background and Objectives: Spiritual health has a positive effect on the organizational behavior of healthcare personnel with patients as well as organizational productivity. Accordingly, the present study aimed to investigate the relationship between spiritual health and job performance of operating room personnel working in the academic hospitals of Qom, Iran, during 2017-2018. Methods: This...