Majid Malekmohammad

Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Pharmaceutical Care Department,Tehran,Iran

[ 1 ] - The effect of amlodipine and sildenafil on the NT-proBNP level of patients with COPD-induced pulmonary hypertension.

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

[ 2 ] - Methacoline Challenge test as an Evaluator of Response to Statins in Bronchial Hyperresponsiveness

3-hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins), are effective serum cholesterol-lowering agents which also have anti-inflammatory properties. The objective of this study was to evaluate the effect of atorvastatin on bronchial hyperresponsiveness. Adult patients (age 14 to 65 years) with bronchial hyperresponsiveness (BHR) diagnosis based on the spirometry with methacholine challe...

[ 3 ] - The effect of amlodipine and sildenafil on the NT-proBNP level of patients with COPD-induced pulmonary hypertension.

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

[ 4 ] - Methacoline Challenge test as an Evaluator of Response to Statins in Bronchial Hyperresponsiveness

3-hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins), are effective serum cholesterol-lowering agents which also have anti-inflammatory properties. The objective of this study was to evaluate the effect of atorvastatin on bronchial hyperresponsiveness. Adult patients (age 14 to 65 years) with bronchial hyperresponsiveness (BHR) diagnosis based on the spirometry with methacholine challe...

[ 5 ] - بررسی روند درمان در بیماران مبتلا به هیپرتانسیون ایدیوپاتیک شریان ریوی (IPAH) بر سطح سرمی NT-ProBNP در بیمارستان دکتر مسیح دانشوری در سال‌های 1392-1390

سابقه و هدف: سطح پپتید ناتریورتیک مغزی (NT-ProBNP) در بیماران مبتلا به هایپرتانسیون ایدیوپاتیک شریان ریوی، متناسب با میزان کاهش عملکرد بطن راست، افزایش می‌یابد. این مطالعه، با هدف بررسی تعیین روند درمان در بیماران مبتلا به هایپرتانسیون ایدیوپاتیک شریان ریوی (IPAH) بر سطح سرمی NT-ProBNP انجام شد. مواد و روش‌ها: این مطالعه از نوع پیگیری طولی روندی، در فاصله‌ی سال‌های 1392-1390 روی 20 بیمار مبتلا ...