صفری, فاطمه

دانشکده پزشکی

[ 1 ] - ایجاد کیندلینگ شیمیایی با استفاده از PTZ و بررسی اثر عصاره آبی گل ماده گیاه رازک بر روند کیندلینگ در موش‌های سوری نر

Introduction: More than 1% of world population suffer from epilepsy, which affects many aspects of individuals’ life. In fact, multiple treatment methods are used for this disorder, among which treatment effects of herbal plants can be introduced. Humulus Lupulus has been utilized in the traditional medicine as an anti-convulsion herb. Therefore, this study aimed to investigate the anti-convuls...

[ 2 ] - بررسی اثر ضد‌تشنجی عصاره آبی دانه تاتوره بر تشنج‌های ناشی از PTZ در موش‌های سوری نر

Background: Epilepsy is one of the most common neurological disorders that affect social, economic and biological aspects of the human life. Many epileptic patients have uncontrolled seizures and medication-related side effects despite adequate pharmacological treatment. The use of plant extracts is proposed as a therapeutic modality in order to treat different diseases. Datura plant has long b...

[ 3 ] - Therapeutic effects of 1,25-dihydroxyvitamin D and losartan co-administration on myocardial ischemia-reperfusion injury in rats

Introduction: Studies support the idea that low levels of vitamin D are associated with a higher risk of heart disease. Losartan has also been prescribed as a drug commonly used for treating hypertension. The aim of the current study was to investigate the effects of 1,25-dihydroxyvitamin D in combination with a non-hypotensive dose of losartan on myocardial infarct size, reperfusion-induced...

[ 4 ] - Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...

[ 5 ] - Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...