Kazemi, Sohrab

Department of Pharmacology, Babol University of Medical Sciences, Babol, Iran.

[ 1 ] - Cadmium toxicity and treatment: An update

Cadmium poisoning has been reported from many parts of the world. It is one of the global health problems that affect many organs and in some cases it can cause deaths annually. Long-term exposure to cadmium through air, water, soil, and food leads to cancer and organ system toxicity such as skeletal, urinary, reproductive, cardiovascular, central and peripheral nervous, and respiratory systems...

[ 2 ] - The HPLC assay of concentration of azithromycin from two different manufacturers in gingival crevicular fluid (GCF)

Background: Azithromycin (AZM) is used in periodontal infections. The present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the HPLC method. Methods: Two groups (n=15) of healthy volunteers participated in this study. The first group received an imported azithromycin (ImAZM) tablet (250 mg, PO) and the second group received an ...

[ 3 ] - اثر نانوذرات کرایزین در جلوگیری از رشد سلول های سرطانی MCF-7

سابقه و هدف: کرایزین یک ترکیب طبیعی و فعال از لحاظ بیولوژیکی است که از گیاهان، عسل و پروپولیس استخراج می‌گردد. از آنجائیکه کرایزین دارای فعالیت­های فارماکولوژیکی از جمله خصوصیات آنتی‌اکسیدانی، ضدالتهابی و ضدسرطانی است. این مطالعه به منظور مقایسه اثر کرایزین و نانوذره آن بر سلولهای سرطان پستان(Michigan Cancer Foundation-7) انجام شد. مواد و روش­ها: در این مطالعه نانوذره کرایزین با استفاده از کیتو...

[ 4 ] - Chemical Composition, Antibacterial and Analgesic Activity of Lavandula stoechas Flowers from North of Iran

Aromatic plants have subscribed to the belief that they can be used in food, perfumery, pharmaceutical and cosmetic products due to their nutritional and biological properties. The present study was designed to examine the chemical composition and antibacterial and analgesic properties of Lavandula stoechas flowers originating Amol, north of Iran for the first time. The essential oil o...

[ 5 ] - Separation of Curcumin from Curcuma longa L. and its Conjugation with Silica Nanoparticles for Anti-cancer Activities

Curcumin is the natural bio-active component of turmeric (Curcuma longa L.) with known therapeutic properties; nevertheless, its biological applications are limited due to its poor bioavailability. To overcome this limitation, curcumin was conjugated with silica nanoparticles. Curcumin was separated from turmeric by microwave-assisted extraction and silica nanoparticles were developed from rice...

[ 6 ] - Therapeutic options to treat mustard gas poisoning – Review

Among the blistering (vesicant) chemical warfare agents (CWA), sulfur mustard is the most important since it is known as the “King of chemical warfare agents”. The use of sulfur mustard has caused serious damages in several organs, especially the eyes, skin, respiratory, central and peripheral nervous systems after short and long term exposure, incapacitating and even killing people and troops....

[ 7 ] - The Effect of Hydroalcoholic Extract of Flaxseed on Bone Mineral Density in Wistar Rats using Digital Radiography

Background: Given that the world's population is aging, the problems associated with osteoporosis and related fractures are increasing. The aim of the study was to evaluate the effect of flaxseed extract on bone mineral density (BMD) in Wistar rats using digital radiography. Methods: In this experimental study, 25 male and 25 female Wistar rats were randomly divided into 5 groups: 1. Control...

[ 8 ] - Sequential Microwave-assisted Extraction for Isolation of Quercetin from Red Kidney Bean

Quercetin is a biological flavonoid, which can be found in red kidney bean at high concentration. In this study, a comparison was conducted between traditional and modern extraction methods. Sequential microwave-assisted extraction was used for isolation of quercetin from red kidney bean. The effect of several factors such as particle size of grinded kidney bean, extraction solvent, microwave p...

[ 10 ] - Protective effect of lycopene on oral mucositis and antioxidant capacity of blood plasma in the rat exposed to gamma radiation

Background: Nowadays, radiotherapy is used effectively for treatment of head and neck cancers. Mucositis is one of the most important side effects of radiotherapy. Radio-protective agents protect tissues and cells against the adverse effects due to ionizing radiation and cleave radiation-induced free radicals. Lycopene as a potent antioxidant protects cells against oxidative damage by free radi...

[ 11 ] - A brief review of the latest pharmacological treatments of COVID-19

New Coronavirus which is called 2019-Novel-Coronavirus (2019-nCoV) or Severe acute respiratory Syndrome-Coronavirus 2 (SARS-Cov-2) causes deadly pneumonia that first appeared in December 2019 in Wuhan city in China. This virus spreads over the world quickly and made several problems to the community and health care system. Several drugs have been tried to manage COVID-19; however, our knowledge...