Bahia Namavar Jahromi
Infertility Research Center, Department of OB-GYN, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
[ 1 ] - Expression of Melanocortin 4 Receptor mRNA in Male Rat Hypothalamus During Chronic Stress
The effects of chronic stress and glucocorticoids receptor antagonist (RU486) on expression of melanocortin 4 receptor (MC4R) mRNA in arcuate nucleus (ARC) of male rats were evaluated. In this study, adult male Sprague Dawley rats were placed into four groups (n=6/group) stress, RU486, stress/RU486, and control groups. In stress group, the rats were restrained, 1 h/day, for 12 days. In RU486 gr...
[ 2 ] - Primary Hydatidosis of Uterus and Left Fallopian Tube
Hydatid cysts are known to occur in most organs especially in the endemic areas. However, its occurrence in uterus is extremely rare and it mostly occurs as a secondary involvement. Herein we reported on a 25-year-old woman with primary involvement of the uterus and left fallopian tube. The patient presented with a colicky abdominal pattern and fever and was admitted to the Emergency Ward.
[ 3 ] - Ovarian Hyperstimulation Syndrome: A Narrative Review of Its Pathophysiology, Risk Factors, Prevention, Classification, and Management
Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction that usually occurs after gonadotropin stimulation, followed by human chorionic gonadotropin administration, for infertility treatment. The existing knowledge about the pathophysiology, risk factors, and primary and secondary methods for the prevention of OHSS is reviewed in this manuscript. The clinical m...
[ 4 ] - The Effect of Four Different Gonadotropin Protocols on Oocyte and Embryo Quality and Pregnancy Outcomes in IVF/ICSI Cycles; A Randomized Controlled Trial
Background: Despite the large number of papers published on the efficiency of different exogenous gonadotropins, no confirmed protocol exists. Therefore, the aim of the present study was to compare the efficacy of 4 exogenous gonadotropins in IVF/ICSI cycles.Methods: This study, performed from January 2014 to May 2014, recruited 160 women referred to Ghadir Mother and Child Hospital and Dena Ho...
[ 5 ] - Effect of Melatonin on the Outcome of Assisted Reproductive Technique Cycles in Women with Diminished Ovarian Reserve: A Double-Blinded Randomized Clinical Trial
Diminished ovarian reserve (DOR) significantly decreases the success rate of the assisted reproductive technique (ART). In this study, we assessed the effect of melatonin on the ART outcomes in women with DOR. A double-blinded, randomized, clinical trial was performed on 80 women with DOR as a pilot study in Shiraz, between 2014 and 2015. DOR was defined as the presence of 2 of the following 3 ...
[ 6 ] - Sublingual versus Vaginal Misoprostol for the Induction of Labor at Term: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial
Background: We sought to compare the effectiveness and safety of sublingual versus vaginal misoprostol for the termination of pregnancy with a live full-term fetus.Methods: This randomized, triple-blind, placebo-controlled clinical trial was performed on 200 primiparous women with normal, singleton, full-term pregnancies candidated for the induction of labor. Sublingual and vaginal tablets cont...
[ 7 ] - A Comprehensive Review about Quercus infectoria G. Olivier Gall
Due to an interaction between gall wasp Andricus sternlichti Bellido and Quercus infectoria G.Olivier from Fagaceae, the oak galls with a wide range of industrial and pharmaceutical applications are produced. Quercus infectoria galls have been well-known by both ethnopharmacology and traditional medicine of Iran. The aim of current study was a comprehensive collection...
[ 8 ] - Founder Effect of KHDC3L, p.M1V Mutation, on Iranian Patients with Recurrent Hydatidiform Moles
Background: Recurrent hydatidiform moles (RHMs) are an unusual pregnancy with at least two molar gestations that are associated with abnormal proliferation of trophoblastic tissue and a failure in the embryonic tissues development. Three maternal-effect genes, including NLRP7, KHDC3L, and PADI6 have been identified as the cause of RHMs. The present study aimed to understand the association of a...
[ 9 ] - A Novel Mutation in NLRP7 Related to Recurrent Hyda-tidiform Mole and Reproductive Failure
Objective Hydatidiform mole (HM) is an abnormal human pregnancy with excessive trophoblastic proliferation and abnormal embryonic development, which is divided into two Complete (CHM) and Partial (PHM) groups. One subcategory of the CHMs is recurrent and familial, which is known as biparental hydatidiform mole (BiHMs) or recurrent hydatidiform mole (RHM). NLRP7 and KHDC3L, two maternal-effect g...
[ 10 ] - Comparing The Effects of Glycyrrhiza glabra Root Extract, A Cyclooxygenase-2 Inhibitor (Celecoxib) and A Gonadotropin-Releasing Hormone Analog (Diphereline) In A Rat Model of Endometriosis
Objective The purpose of this study was to compare the effects of Glycyrrhiza glabra (Licorice), Cyclooxygenase-2 Inhibitor (Celecoxib®) and gonadotropin releasing hormone analog (Diphereline®) to a control group on endometrial implants in rats. MaterialsAndMethods Endometriosis was induced in rats by auto transplantation and after confirmation, the rats were divided into 4 groups that were tre...
[ 11 ] - Detection of Y Chromosome Microdeletions and Hormonal Profile Analysis of Infertile Men undergoing Assisted Reproductive Technologies
Objective Y chromosome deletions (YCDs) in azoospermia factor (AZF) region are associated with abnormal spermatogenesis and may lead to azoospermia or severe oligozoospermia. Assisted reproductive technologies (ART) by intracytoplasmic sperm injection (ICSI) and testicular sperm extraction (TESE) are commonly required for infertility management of patients carrying YCDs. The aim of this study w...
[ 12 ] - Quality of Life and Its Influencing Factors of Couples Referred to An Infertility Center in Shiraz, Iran
Objective Infertility has an adverse effect on Quality of Life (QoL). The present study aimed to evaluate QoL and its effective factors in infertile couples. MaterialsAndMethods Fertility Quality of Life (FertiQoL) Instrument was used to measure QoL among 500 volunteer couplesattending the infertility clinic of Mother and Child Hospital in Shiraz, Iran. The participants’ demographic and clinica...
[ 13 ] - Predicting Implantation Outcome of In Vitro Fertilization and Intracytoplasmic Sperm Injection Using Data Mining Techniques
Objective The main purpose of this article is to choose the best predictive model for IVF/ICSI classification and to calculate the probability of IVF/ICSI success for each couple using Artificial intelligence. Also, we aimed to find the most effective factors for prediction of ART success in infertile couples. MaterialsAndMethods In this cross-sectional study, the data of 486 patients are colle...
[ 14 ] - P-4: Effect of Chronic Stress on Stereological Properties of Seminiferous Tubules in Adult Male Rats
Background Male fertility and reproduction can affect by stress. The means by which stress influences reproduction is not clearly understood. The aim of the present study was to examine, using stereological methods, the role of glucocorticoids during chronic restraint stress on spermatogenesis. MaterialsAndMethods Twenty four male adult Sprague- Dawley rats were allocated to four equal groups; ...
[ 15 ] - P-21: RF-Amide Related Peptide mRNA Expression in Male Rat Dorsomedial Hypothalamic Nucleus during Chronic Stress
Background Chronic stress induces male reproductive dysfunction; however, the involved mechanisms are not clear. It has been suggested that the gonadotrophin-inhibitory hormone, known as RF-amide related peptide (RFRP) in mammalian species, may mediate this inhibitory effect of stress. The objective of the present study was to compare the effect of chronic stress and glucocorticoids receptor an...
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