SOMAYYEH KARAMI-MOHAJERI

Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

[ 1 ] - Inhibitory effect of concomitant administration of Zataria multiflora Boiss. against oxidative damage-induced by sub-acute exposure to arsenic in rats

To evaluate the protective effect of Zataria multiflora boiss. (Zm) extract against arsenic-induced oxidative damage in rats. Rats were orally treated with various doses of Zm (200, 400, and 600 mg/kg) and sodium arsenite (5.5 mg/ kg), alone or in combination, once daily for 30 consecutive days. Twenty-four hours after the last dose, rats were euthanized, and biochemical studies were conducted ...

[ 2 ] - Malathion-increased Hepatotoxicity in Diabetic Rats

Background: Malathion (MT), an organophosphorus pesticide, induces hepatotoxicity and is associated with hyperglycemia and the development of diabetes mellitus.  Objectives: This study was aimed to evaluate the effects of sub-acute exposure to sub-lethal dose of MT in the liver of diabetic rats.  Methods: Non-diabetic and streptozotocin-induced diabetic rats received MT at a dose of 150 mg/kg...

[ 3 ] - Sub-acute Exposure to Benzene Accelerates the Aging Process of Red Blood Cells; an In vivo Study

Background: The well-known toxic effects of benzene toxicity are bone marrow depression, reduction in blood cell counts, and induction of leukemia and aplastic anemia. This study was designed to evaluate biomarkers of aging in red blood cells (RBCs). Methods: Mice were exposed to benzene (50, 100, and 200 mg/kg/day) orally for 28 days. A group of benzene-exposed mice were injected intraperiton...

[ 4 ] - Effect of vitamin D administration on blood oxidative stress factors in university students: A randomized double-blind clinical trial

Introduction: Vitamin D deficiency is widespread in the world and is prevalent in Muslim countries despite sufficient sunlight. Vitamin D deficiency disrupts mitochondrial function and enhances oxidative stress and leads to common diseases such as metabolic disorders. This study aimed to evaluate the efficacy of vitamin D supplementation on oxidative stress factors in students. Materials and Me...