Zhaleh Karimi Moghaddam

Department of Radiation Oncology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

[ 1 ] - The Epidemiological Survey of the Cancer Patients Referring to the Radiotherapy Center at Vali-e-Asr Teaching Hospital in Zanjan, Iran (2016-2018)

Background: Cancer is defined as the uncontrolled growth of abnormal cells and the second most common cause of death across the world. More than half of new cancer cases are reported in developing countries, the prevalence of cancer is on the rise in these countries due to the lifestyle risk factors associated with cancer. It is predicted that cancer will become the main cause of death worldwid...

[ 2 ] - A Patient with Acroangiodermatitis Without a History of Vascular Disease: A Case Report

Acroangiodermatitis (AAD), also known as Pseudo-Kaposi’s sarcoma, is a rare benign angioproliferative disease associated with chronic venous insufficiency (CVI) or other vascular disorders. We present an 81-year-old male with plaque-like cutaneous lesions, which had progressive erythematous margins, severe pain, and intense pruritus, as well as bilateral swollen and painful feet. It was around ...

[ 3 ] - Association between Polymorphisms of X-ray Repair Cross Complementing 5 and 6 Promoter Genes and the Risk of Metastatic Breast Cancer

Background and Objective: Breast cancer is the second leading cause of cancer-related death in women. Better individualized treatment needs novel prognostic predictors. X-ray repair cross complementing XRCC5 and XRCC6 are coding genes of the Ku protein complex (key components of the non-homologous end-joining [NHEJ] pathway), which could serve as prognostic factors in breast cancer. Hence, in t...

[ 4 ] - CXCL12/CXCR4 Gene Polymorphism as a Putative Prognostic Factor for Metastasizing Breast Cancer under Chemotherapy

The receptor and the receptor axis CXCL12 / CXCR4 are the two pairs studied in the metastasis of breast cancer. The purpose of this study was to investigate the relationship between the occurrence of CXCR4 / CXCL12 genes polymorphism and the clinical and pathological characteristics of patients with metastatic breast cancer under chemotherapy. Material and methods: Genomic DNA was extracted f...

[ 5 ] - Effectiveness of muscle strengthening exercises on the clinical outcomes of patients with knee osteoarthritis: A randomized four-arm controlled trial

Background: Knee osteoarthritis (OA) is one of the major causes of dysfunction that reduces patients’ quality of life. The aim of current study was to investigate the effectiveness of muscle strengthening exercises on the clinical outcomes of patients with knee OA. Methods: We conducted a single-blind clinical trial on 96 patients with mild to moderate knee osteoarthritis. Patients were random...