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گروه آموزشی علوم آزمایشگاهی دانشکده پیراپزشکی دانشگاه علوم پزشکی تهران.

[ 1 ] - مقایسه تغییرات لیپیدهای سرم در بیماران مبتلا به لوسمی‌های حاد قبل و بعد از شیمی درمانی

مقدمه تحقیقات موجود بیانگر اختلالات لیپیدهای سرم در انواع سرطان ها میباشد. همچنین مطالعاتی در مورد وضعیت لیپیدهای سرم در بیماران مبتلا به سرطان خون و ارتباط آن با فعالیت بیماری و نحوه پاسخ به شیمی درمانی صورت گرفته است. هدف از این مطالعه بررسی پروفایل لیپیدی بیماران مبتلا به لوسمی حاد قبل و بعد ازدرمان می باشد.  روش کار جمعیت مورد مطالعه 78 نفر از بیماران مبتلا به لوسمی های حاد مراجعه کننده ...

[ 2 ] - پروتئین های شبه آنژیوپوئیتین

چاقی و بیماری های متابولیک مربوطه مانند دیابت نوع 2، فشار خون بالا و هیپرلیپیدمی و در نتیجه، افزایش خطر ابتلا به بیماری های قلبی- عروقی از مسائل شایع پزشکی و اجتماعی در کشورهای توسعه یافته و در حال توسعه است. بنابراین درک اساس مولکولی زمینه ای چاقی و بیماری های متابولیک مربوط به آن به منظور توسعه پیشگیری و روش های درمانی موثر در مقابل چنین شرایطی دارای اهمیت است. آنژیوپوئتین (angpt) عضوی از خا...

[ 3 ] - Evaluation of the Effects of Morphine on Sex Hormones in Wistar Rats

Background and Aim:Morphine is one of the most important alkaloids of opium family that is the most effective combintion of family as well. Morphine is a narcotic analgesic and is very strong. Due to the use of morphine and its derivatives, applying the effect of this substance on the body's hormones, especially sex hormones is very important. The aim of this study was to investigate the effect...

[ 4 ] - Copeptin,as a new Boimarker

everything that disturbs the homeostatic balance of the body can be defined as stress and any stress factor activating the hypothalamic- pituitary-adrenal (HPA) axis causes an increase in arginine vasopressin (AVP) plasma concentrations. AVP is a 9 amino acid peptide in the ring structure and derived from pre-pro vasopressin. Pre-pro vasopressin is a pro hormone that synthesized by supraoptic ...

[ 5 ] - Klotho Protein,A Biomarker for AKI

Klotho is an anti-aging single-pass membrane protein that is mainly produced in the kidney. The level of soluble klotho decreases with age and the klotho gene is associated with an increased risk of age-related diseases, such as diabetes, skin atrophy, chronic kidney disease, ataxia and cancer. The klotho gene is composed of five exons and encodes a membrane glycoprotein located in the plasma ...

[ 6 ] - Evaluation of structure of paraoxonase (PON) and its relationship with various diseases

The paraoxonase family in humans includes the PON1, PON2, and PON3 genes. These genes are located on the long arm of chromosome 7 and are structurally similar .Between the nucleotide sequences of these three genes is about 70% and between their amino acid    sequences is about 60% compatibility. The three have 9 exons, which in the case of PON1 exists an addition code in position 106 (lysine) i...

[ 7 ] - Effects of Taurine, Sestrin 2 and Phyllanthin on coronary artery diseases

Heart failure is a growing epidemic in the worldwide. Atherosclerosis is a major mechanism of cardiovascular disease including myocardial infarction and peripheral arterial disease. Moreover, it causes many diseases and deaths around the world. Atherosclerosis, like coronary artery disease (CAD), is associated with inflammation and oxidative stress. The current article has been collected the s...

[ 8 ] - Association of serum melatonin and albumin with cardiovascular disease

Cardiovascular diseases are a major cause of death worldwide.  Endothelial dysfunction, inflammatory conditions, and oxidative stress at the forefront of the onset and progression of most cardiovascular diseases specificaly coronary heart disease and heart failure. Melatonin is a type of indole neuroendocrine hormone.  It was first found that the regulation of the sleep-wake cycle is regulated...

[ 9 ] - Evaluation of Serum Levels of Mannose Binding Lectin-2, Tenascin-C in Patients with Coronary Artery Disease (CAD)

Cardiovascular disease (CVD) is a leading cause of death worldwide and continues to increase in prevalence compared to previous decades, in part because of the aging of the world population. Atherosclerotic CVD starts at a very young age and progresses over time allowing sufficient time for screening and early detection of the condition. Advances in biomarker research and developments related t...