OBJECTIVE To evaluate the use of anti-obesity drugs among students attending a public university. METHODS This was a cross sectional random study of 664 college students. Drug use, socioeconomic, and anthropometric variables were observed. Body mass index (BMI) and waist circumference (WC) were classified according to World Health Organization criteria. RESULTS Current or previous use of an...

Adipose tissue secretes many adipokines that regulate important physiological functions. Growing studies have highlighted these bioactive molecules may contribute to the development of metabolic and cardiovascular diseases. Adipokines exert systemic effects independent activity on numerous cells system, including cardiomyocytes vascular cell walls. Adiponectin shows anti-inflammatory anti-ather...

Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are associated with an increased incidence and mortality from many cancers. The metabolic abnormalities associated with type 2 diabetes develop many years before the onset of diabetes and, therefore, may be contributing to cancer risk before individuals are aware that they are at risk. Multiple factors potential...

In this chapter we review the role and potential benefits of non-caloric sweeteners, as part of the diet. After appearing and interest in the beneficial effects attributed to them, face different situations and conditions (obesity, diabetes...), more and more numerous studies, show their ineffective use. In conclusion, further research and results are needed to provide convincing evidence of th...

Clinical management of obese subjects to reduce their risk of suffering cardiovascular events is complex. Obese patients typically require preventive strategies, life-style modifications, and multi-drug therapy to address obesity-induced co-morbidities. Data regarding the effects of excess weight on the pharmacokinetics of most drugs is scarce as these individuals are often excluded from clinic...

Peripherally active anorectic agents represent a new approach to the pharmacological management of obesity. Two inhibitors of carbohydrate absorption: an alpha-glucosidase inhibitor, acarbose (Bay g 5421) and a alpha-amylase inhibitor, Ro 12-2272, were compared with two novel inhibitors of lipid metabolism: an inhibitor of human pancreatic lipase (Ro 20-0083) and of hepatic fatty acid synthesis...

Antipsychotic medications, which comprise one of the most widely prescribed medication classes, have proven effective in many psychiatric conditions. However, these agents can also be associated with obesity and other metabolic abnormalities, the mechanisms of which have been partially elucidated. We review here the current state of knowledge of the effects of these medications on weight and ap...

During the worldwide COVID-19 outbreak, there was an increase in prevalence of obesity, including childhood due to which awareness obesity and interest treatment increased. Accordingly, we describe EJF (Euscaphis japonica Kanitz fruit) extract as a candidate for naturally derived antiobesity agents. In this study, found that is involved early stage adipogenic differentiation vitro finally inhib...

Background: Non-communicable diseases (NCDs) are medical conditions or illnesses that not caused by infectious agents. Modifiable behavioural risk factors, such as tobacco use, physical inactivity, unhealthy diet, stress and the harmful use of alcohol metabolic hypertension, diabetes, dyslipidemia, obesity, increase stroke. Strokes in Asian patients account for more than two-thirds overall stro...

Objective of the Review: To present pathophysiological mechanisms coronavirus infection in obese patients, and approaches to obesity correction this group patients following an overview large randomized clinical trials cardiovascular safety from PubMed, Cochrane Library, Google Scholar. Key Points. Clinical have demonstrated that is a significant risk factor number comorbidities, including seve...