Autism spectrum disorder (ASD) is associated with disruption of local- and long-range functional connectivity (FC). The direction of those changes in FC (increase or decrease), however, is inconsistent across studies. Further, age-dependent changes of distance-specific FC in ASD remain unclear. In this study, we used resting-state functional magnetic resonance imaging data from sixty-four typic...

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and communication, and restricted, repetitive patterns of behavior. In order to identify individuals with ASD and initiate interventions at the earliest possible age, biomarkers for the disorder are desirable. Research findings have identified widespread changes in the immune syste...

Ostium secundum atrial septal defect (ASD) is a common congenital heart defect. The adverse prognosis of untreated ASD diagnosed in childhood is well studied and percutaneous device closure of these ASDs has evolved to become the standard of care in both pediatric and young adult populations. There is a growing body of literature that suggests the benefits of ASD closure are not restricted to y...

Reduced focus toward the eyes is a characteristic of atypical gaze on emotional faces in autism spectrum disorders (ASD). Along with the atypical gaze, aberrant amygdala activity during face processing compared with neurotypically developed (NT) participants has been repeatedly reported in ASD. It remains unclear whether the previously reported dysfunctional amygdalar response patterns in ASD s...

This article reviews the literature reporting on trainings implemented with children Autism Spectrum Disorder (ASD) without intellectual disability to enhance their capability cope metaphor comprehension. The studies in this review can be classified into two main strands of thought, behavioral-analytic and psycholinguistic, respectively. Beyond some basic similarities all these share attempt at...

Facial expressions in sign language carry a variety of communicative features. While emotion can modulate a spoken utterance through changes in intonation, duration and intensity, in sign language specific facial expressions presented concurrently with a manual sign perform this function. When deaf adult signers cannot see facial features, their ability to judge emotion in a signed utterance is...

Abstract Objective The sequelae of poor attachment and trauma on psychological social functioning is well documented, however, this complex relationship applied to a neuropsychological profile less understood. current case uses assessment further understand the brain-behavior in maternal attachment, multiple traumas, psychiatric comorbidities, adaptation. Method Patient 22-year-old, right-hande...

Background: The diagnosis rate of adult spinal deformity (ASD) is increasing with increased life expectancy and the prevalence degenerative diseases. ASD in adults aged >60 years has been reported to be up 68%. significant impact on pain, disability, mental health. Therefore, it necessary establish an effective surgical plan by accumulating modern knowledge ASD, developing techniques, improv...

BACKGROUND Patients with fever and rash often pose an urgent diagnostic and therapeutic dilemma for the clinician. The nonspecificity of many fever and rash syndromes mandates a systemic approach to diagnosis. OBJECTIVE We aimed to determine the etiology of fever and rash in 100 adult patients followed-up as in- or outpatients prospectively. METHODS All the patients, who presented with rash...

BACKGROUND Recent studies point to overlap between neuropsychiatric disorders in symptomatology and genetic aetiology. AIMS To systematically investigate genomics overlap between childhood and adult attention-deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and major depressive disorder (MDD). METHOD Analysis of whole-genome blood gene expression and genetic risk scores...