Introduction/Background The pathological changes at different severity stages of cervical intraepithelial neoplasia (CIN) can give rise to the differences in electrical properties tissues, which lay foundation for screening CIN using non-invasive and cost-effective technique bioimpedance as well paves way easy availability screening, especially developing countries thereby reduction oc...

OBJECTIVE To evaluate the efficacy of 1% topical cidofovir cream for the treatment of anal high-grade squamous intraepithelial lesions (HSILs) in HIV-infected individuals. DESIGN Single-arm, open-label, pilot clinical trial. METHODS The study medication was applied intraanally three times per week for 4 weeks. Lesions were assessed with high-resolution anoscopy and biopsy at weeks 12 and 24...

Background : We examined cervicovaginal smears that contained definite low-grade squamous intraepithelial lesion (LSIL) cells and rare atypical cells suggestive of high-grade SIL (HSIL) (ASC-H) or contained borderline dysplastic cells between LSIL and HSIL. Such lesions were classified as LSIL-H. This study aimed to investigate the cytologic and histologic characteristics of LSIL-H category and...

BACKGROUND HIV-positive women have a high prevalence of human papillomavirus (HPV) infection and are infected with a broader range of HPV types than HIV-negative women. It is not known to what extent these different types are associated with high-grade squamous intraepithelial lesions (HSIL) and cancer. METHODS Meta-analysis of HPV type-specific prevalence among HIV-positive women, stratified...

OBJECTIVES To determine how human papillomavirus (HPV) positivity of atypical glandular cells (AGCs) affects the predictive values for the presence of high-grade cervical lesions. DESIGN Population-based cohort study. SETTING Stockholm-Gotland region, Sweden. PARTICIPANTS Between 17 February 2014 and 30 June 2016, there were 562 women with AGC detected in a cervical sample. Registry linka...

Materials and methods: A total of 3488 women who were undergoing routine cervical screening (1308 CC and 2180 LBC) were included in the initial screening. The results were assessed as either satisfactory or unsatisfactory. Satisfactory results were subdivided as negative, atypical squamous cells of undetermined significance (ASCUS), atypical squamous cells for which high-grade lesions could not...

OBJECTIVE Nucleolar organizer region (NOR) associated proteins are argyrophilic and visualized by silver stains. AgNOR pleomorphic dots increase in cancer and most researchers have done a common count of single dots. Pleomorphic dots are few and perhaps indicate a more severe prognosis. The present study was aimed at investigating the relative preponderance and diagnostic value of both pleomorp...

Liquid Based Cytology (LBC) has replaced Papanicolaou standard cytology due to its practical advantages. Our study aimed to analyze the diagnosis correlations and differences between the conventional and liquid based cytology. The study group has been composed by 104 patients, diagnosed in the Laboratory of Cytology, Galati County Hospital, Romania by using both methods on the same patients gro...

Adequate follow-up and treatment of women with high-grade squamous intraepithelial lesion (HSIL) and cancer is key in reducing cervical cancer mortality. This research study aims to analyze the magnitude of abandonment in the follow-up and treatment process, as well as the reasons for this abandonment, in women with HSIL who received care in public health services in the province of Jujuy in 20...

Background . Current issues in the cytological assessment of cervical epithelium can hamper differential diagnosis high-grade squamous intraepithelial lesion (HSIL) and cancer. Aim To determine informativity locally estimated values odd-numbered higher fatty acids as markers HSIL Materials methods. Previous original data on content biopsy primary pre-treatment cancer patients were analysed retr...