objective(s): pei based nanoparticle (np) due to dual capabilities of proton sponge and dna binding is known as powerful tool for nucleic acid delivery to cells. however, serious cytotoxicity and complicated conditions, which govern nps properties and its interactions with cells practically, hindered achievement to high transfection efficiency. here, we have tried to optimize the properties of ...

objective(s): our previous studies have shown that mgo nanoparticles (mgo nps) could improve anxiety and reduce pain in animals. in this study, the effect of co administration mgo nps and vitamin c on anxiety like behavior and nociception in postpartum depression (ppd) model were investigated.materials and methods:  female mice (27 ± 3 g) were divided into groups: two control groups, ppd groups...

background: migarine is the most common headache around the world including iran. in recent years, vitamin d deficiency has been shown to a global health problem. a few studies have been determined inverse association between serum levels of vitamin d with a headache. so, in this study, we investigated the effect of vitamin d supplementation on symptoms and c-reactive protein(crp) among patient...

The present study was aimed to test the efficacy of adding vitamins C or E to Tris-fructose-egg yolk diluent to increase Awassi ram sperm storage period at 5 ˚C. Semen samples from six mature Awassi rams were used in this study. The semen samples were diluted by Tris-glucose-egg yolk. Diluted semen sample was divided into three parts. The first part was added with 0.9 mg mL-1 vitamin...

oxidative stress mediated by reactive oxygen species is known to contribute to the inflammatory process of bronchial asthma. reactive oxygen species are released into the bronchial tree by activated inflammatory cells. in this study, we aimed to determine the effect of vitamin c administration on leukocyte vitamin c level as well as severity of asthma. in this double blind clinical trial study ...

background: in the last decades, mesoporous silica nanoparticles (msn) are improved for drug delivery, imaging, and biomedical applications due to their special properties such as large surface area, high drug loading capacity, tunable pore size, and modification of surface area by functional groups. objectives: the aim of this study was to evaluate msns as carriers for oral colon-specific and ...

background and purpose: vitamin c is administered orally or intravenously for the treatment of burn wounds. however, effects of the topical application of vitamin c remain unclear. this study aimed to evaluate the effects of topical vitamin c solution on the necrotic tissue volume of second-degree burn wounds. methods: this clinical trial was conducted on 30 patients with second-degree burns ad...

The effects of dietary supplementation of grape seed extract (GSE) and vitamin C on carcass characteristics, gut morphology and ileal microflora in broiler chickens exposed to chronic heat stress were examined. Experimental diets included a control diet (without additive), 3 levels of GSE (150, 300, 450 mg/kg of diet), and vitamin C (300 mg/kg of diet). Each of the five diets was fed to 5 repli...